Poly(3-hydroxybutyrate) [P(3HB)] and other polyhydroxyalkanoates (PHAs) have been drawing much attention as biodegradable substitutes for conventional nondegradable plastics. For the economical production of P(3HB), various bacterial strains, either wild-type or recombinant, and new fermentation strategies were developed for the production of P(3HB) with high concentration and productivity. To reduce the cost of carbon substrate, several processes for P(3HB) production from cheap carbon sources were also developed. P(3HB) can now be produced to a content of 80% of cell dry weight with the productivity greater than 4 g/l per h. Fermentation strategy was also developed for the efficient production of medium chain length PHA by high cell density culture. With all these advances, P(3HB) and PHAs can be produced by bacterial fermentation at a cost (ca.
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机译：聚（3-羟基丁酸酯）[P（3HB）]和其他聚羟基链烷酸酯（PHA）作为常规不可降解塑料的可生物降解替代品备受关注。为了经济地生产P（3HB），已开发了多种野生型或重组细菌菌株，并开发了新的发酵策略来生产高浓度和高生产率的P（3HB）。为了降低碳基材的成本，还开发了几种从廉价碳源生产P（3HB）的方法。现在可以生产出P（3HB），占细胞干重的80％，生产率大于每小时4 g / l。还开发了发酵策略，以通过高细胞密度培养有效生产中等链长的PHA。通过所有这些进步，可以通过细菌发酵以一定的成本生产P（3HB）和PHA（约
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