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Transmission Electron Microscopy Studies of Cellular Responses to Entry of Virions: One Kind of Natural Nanobiomaterial

机译:细胞对病毒粒子进入反应的透射电子显微镜研究:一种天然的纳米生物材料。

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摘要

Virions are one kind of nanoscale pathogen and are able to infect living cells of animals, plants, and bacteria. The infection is an intrinsic property of the virions, and the biological process provides a good model for studying how these nanoparticles enter into cells. During the infection, the viruses employ different strategies to which the cells have developed respective responses. For this paper, we chose Bombyx mori cypovirus 1 (BmCPV-1) interactions with midgut cells from silkworm, and severe acute respiratory syndrome (SARS) associated coronavirus interactions with Vero E6 cells, as examples to demonstrate the response of eukaryotic cells to two different types of virus from our previous studies. The bacteriophage-bacteria interactions are also introduced to elucidate how the bacteriophage conquers the barrier of cell walls in the prokaryotic cells to transport genome into the host.
机译:病毒体是一种纳米级病原体,能够感染动物,植物和细菌的活细胞。感染是病毒粒子的固有特性,生物学过程为研究这些纳米粒子如何进入细胞提供了良好的模型。在感染过程中,病毒采用不同的策略,细胞对此产生了相应的反应。在本文中,我们选择家蚕丝状病毒1(BmCPV-1)与家蚕中肠细胞的相互作用,以及重症急性呼吸综合征(SARS)相关的冠状病毒与Vero E6细胞的相互作用,以举例说明真核细胞对两种不同的反应我们以前的研究中的病毒类型。还介绍了噬菌体与细菌的相互作用,以阐明噬菌体如何克服原核细胞中细胞壁的屏障,从而将基因组转运到宿主中。

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