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首页> 外文期刊>International Journal of Biological Macromolecules: Structure, Function and Interactions >Bioactive and metal uptake studies of carboxymethyl chitosan-graft-D-glucuronic acid membranes for tissue engineering and environmental applications
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Bioactive and metal uptake studies of carboxymethyl chitosan-graft-D-glucuronic acid membranes for tissue engineering and environmental applications

机译：羧甲基壳聚糖-D-葡萄糖醛酸膜的生物活性和金属吸收研究，用于组织工程和环境应用

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摘要

Carboxymethyl chitosan-graft-D-glucuronic acid (CMCS-g-D-GA) was prepared by grafting D-GA onto CMCS in the presence of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC) and then the membranes were made from it. In this work, the bioactivity studies of CMCS-g-D-GA membranes were carried out and then characterized by SEM, CLSM, XRD and FT-IR. The CMCS-g-D-GA membranes were found to be bioac_tive. The adsorption of Ni~(2+), Zn~(2+) and Cu~(2+) ions onto CMCS-g-D-GA membranes has also been investigated. The maximum adsorption capacity of CMCS-g-D-GA for Ni~(2+), Zn~(2+)and Cu~(2+) was found to be 57, 56.4 and 70.2 mg/g, respectively. Hence, these membranes were useful for tissue engineering, environmental and water purification applications.
机译：通过在1-乙基-3-（3-二甲基氨基丙基）碳二亚胺（EDC）存在下将D-GA接枝到CMCS上来制备羧甲基壳聚糖接枝D-葡萄糖醛酸（CMCS-gD-GA），然后制成膜从中。在这项工作中，进行了CMCS-g-D-GA膜的生物活性研究，然后通过SEM，CLSM，XRD和FT-IR进行了表征。发现CMCS-g-D-GA膜具有生物活性。还研究了Ni〜（2 +），Zn〜（2+）和Cu〜（2+）离子在CMCS-g-D-GA膜上的吸附。 CMCS-g-D-GA对Ni〜（2 +），Zn〜（2+）和Cu〜（2+）的最大吸附容量分别为57、56.4和70.2 mg / g。因此，这些膜可用于组织工程，环境和水净化应用。

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