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首页> 外文期刊>International Journal of Biological Macromolecules: Structure, Function and Interactions >Chemical analysis of Agaricus blazei polysaccharides and effect of the polysaccharides on IL-1β mRNA expression in skin of burn wound-treated rats
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Chemical analysis of Agaricus blazei polysaccharides and effect of the polysaccharides on IL-1β mRNA expression in skin of burn wound-treated rats

机译：姬松茸多糖的化学分析及多糖对烧伤创面大鼠皮肤IL-1βmRNA表达的影响

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摘要

Agaricus blazei polysaccharides were analyzed by GC-MS. Results indicated that the polysaccharides contained glucose (93.87%), mannose (3.54%), and arabinose (2.25%). The compositional analysis was completed by the methylation data. These data indicated that Agaricus blazei polysaccharides are glucans. Compared to model rats, rats fed with Agaricus blazei polysaccharides showed a decrease of ratio of IL-1β/β-actin and IL-1β level in skin of burn wound. Recovery rate of wound skin increased with increasing dose of polysaccharides. The results indicated that Agaricus blazei polysaccharides could be useful in promote burn wound healing.
机译：通过GC-MS分析了姬松茸多糖。结果表明，多糖包含葡萄糖（93.87％），甘露糖（3.54％）和阿拉伯糖（2.25％）。通过甲基化数据完成组成分析。这些数据表明姬松茸多糖是葡聚糖。与模型大鼠相比，饲喂姬松茸多糖的大鼠在烧伤创面皮肤中的IL-1β/β-肌动蛋白比率和IL-1β水平降低。伤口皮肤的恢复率随多糖剂量的增加而增加。结果表明姬松茸多糖可用于促进烧伤创面愈合。

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