Prospective of guar gum and its derivatives as controlled drug delivery systems

Prabaharan M.

首页> 外文期刊>International Journal of Biological Macromolecules: Structure, Function and Interactions >Prospective of guar gum and its derivatives as controlled drug delivery systems

【24h】

Prospective of guar gum and its derivatives as controlled drug delivery systems

机译：瓜尔胶及其衍生物作为药物控制系统的前景

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Guar gum is a non-ionic polysaccharide that is found abundantly in nature and has many properties desirable for drug delivery applications. However, due to its high swelling characteristics in aqueous solution, the use of guar gum as delivery carriers is limited. Guar gum can be modified by derivatization, grafting and network formation to improve its property profile for a wide spectrum of biomedical applications. This review article is aimed at focusing the recent efforts and developments on guar gum and its derivatives as colon-specific, antihypertensive, protein and transdermal drug delivery systems. Based on the literatures reviewed, it is concluded that guar gum and its derivatives in the various forms such as coatings, matrix tablets, hydrogels and nano/microparticles can be exploited as potential carriers for targeted drug delivery.

机译：瓜耳胶是一种非离子型多糖，在自然界中含量很高，并且具有许多药物输送应用所需的特性。然而，由于其在水溶液中的高溶胀特性，限制了瓜耳胶作为递送载体的使用。瓜尔胶可以通过衍生化，接枝和网络形成进行改性，以改善其在各种生物医学应用中的性能。这篇综述文章旨在聚焦瓜尔胶及其衍生物作为结肠特异性，降压，蛋白质和透皮给药系统的最新努力和发展。根据已审查的文献，得出的结论是，瓜尔胶及其各种形式（如包衣，基质片剂，水凝胶和纳米/微粒）的衍生物可被用作靶向药物递送的潜在载体。

著录项

来源
《International Journal of Biological Macromolecules: Structure, Function and Interactions》 |2011年第2期|共8页
作者
Prabaharan M.;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类生物大分子的结构和功能;
关键词
Colon targeting; Drug delivery; Galactomannan; Guar gum; Hydrogels;

机译：结肠靶向;药物输送;半乳甘露聚糖;瓜尔胶;水凝胶;

相似文献

外文文献
中文文献
专利

1. Prospective of guar gum and its derivatives as controlled drug delivery systems [J] . Prabaharan M. International Journal of Biological Macromolecules: Structure, Function and Interactions . 2011,第2期

机译：瓜尔胶及其衍生物作为药物控制系统的前景
2. DESIGN AND EVALUATION OF COLON SPECIFIC DRUG DELIVERY OF NAPROXEN SODIUM USING GUAR GUM AND CROSSLINKED GUAR GUM [J] . K.RAJYA LAKSHMI, Y.INDIRA MUZIB, VIJAYA KUMAR.VOLETI International Journal of Pharmacy and Pharmaceutical Sciences . 2012,第Suppla1期

机译：瓜尔胶和交联瓜尔胶的萘普生钠结肠给药的设计与评价。
3. In vitro drug release studies on guar gum-based colon targeted oral drug delivery systems of 5-fluorouracil. [J] . Krishnaiah YS, Satyanarayana V, Dinesh Kumar B, European journal of pharmaceutical sciences . 2002,第3期

机译：对基于瓜尔豆胶的结肠靶向5-氟尿嘧啶口服药物递送系统的体外药物释放研究。
4. Design and Development of Guar Gum Matrix Tablets for Controlled and Site Specific Drug Delivery to the Colon [C] . Chourasia Manish Kumar, Jain Sanjay Kumar, Jain Aviral Annual meeting exposition of the Controlled Release Society . 2005

机译：瓜尔胶基质片剂的设计与开发，可控和定点向结肠输送药物
5. The application of controlled radical polymerization processes on the graft copolymerization of hydrophobic substituents onto guar gum and guar gum derivatives. [D] . Holmes, Veronica K. 2007

机译：受控自由基聚合工艺在疏水取代基接枝共聚到瓜尔胶和瓜尔胶衍生物上的应用。
6. Sonication-Based Improvement of the Physicochemical Properties of Guar Gum as a Potential Substrate for Modified Drug Delivery Systems [O] . Siddique Akber Ansari, Pietro Matricardi, Claudia Cencetti, 2006

机译：基于超声处理的瓜尔胶作为改良药物释放系统的潜在底物的理化性质的改进
7. Sonication-based improvement of the physicochemical properties of Guar Gum as a potential substrate for modified drug delivery systems. [O] . Ansari SA, Matricardi P, Cencetti C, 2013

机译：基于超声处理的瓜尔胶的物理化学性质改进，可作为改良药物递送系统的潜在底物。

Prospective of guar gum and its derivatives as controlled drug delivery systems

摘要

著录项

相似文献

相关主题

期刊订阅