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Biogenic silver nanoparticles synthesised from Zingiher officinale and Its antifungat properties

机译:姜皮生物合成的银纳米颗粒及其抗真菌性能

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摘要

A silver particle at the nanoscale level behaves as an effective antimicrobial agent and offers numerous applications in biosensing and medicine. The current study unveils the effect of rhizome of Zingiber officinale and its silver nanoparticles against the growth and hydrolytic enzyme of two lethal moulds, Alternaria alternata and Curvularia lunata. The rhizome of Zingiber officinale was extracted under aseptic conditions to get cold distilled water and silver nanoparticle extracts in order to check the effect on inhibition of cell mass formation and protease activity of Curvularia lunata and Alternaria alternata. The formation of silver nanoparticles was confirmed by UV-Vis absorption spectroscopy and scanning electron microscopy. The obtained results showed that the highest tested concentration (2%) of Zingiber officinale in cold distilled water and silver nanoparticle extracts strongly inhibited the cell mass formation as well as protease activity in test organisms. The silver nanoparticle extract showed potent antifungal activity when compared to cold distilled water extract. The study unravels the antifungal property of Zingiber officinale and its biogenically synthesised silver nanoparticles that can be exploited further for therapeutical and other industrial applications.
机译:纳米级的银颗粒可作为有效的抗菌剂,并在生物传感和医学中提供众多应用。目前的研究揭示了姜黄及其银纳米颗粒的根茎对两种致命霉菌链格孢和弯孢霉的生长和水解酶的影响。在无菌条件下提取姜皮的根茎,得到冷蒸馏水和银纳米颗粒提取物,以检查对弯孢和链格孢的细胞团形成和蛋白酶活性的抑制作用。通过UV-Vis吸收光谱法和扫描电子显微镜确认了银纳米颗粒的形成。获得的结果表明,冷蒸馏水和银纳米颗粒提取物中的最高生姜浓度(2%)强烈抑制了被测生物中细胞的形成以及蛋白酶的活性。与冷蒸馏水提取物相比,银纳米颗粒提取物显示出有效的抗真菌活性。这项研究揭示了姜和其生物合成的银纳米颗粒的抗真菌特性,可以进一步用于治疗和其他工业应用。

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