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首页> 外文期刊>British journal of ophthalmology >The contribution of low birth weight to severe vision loss in a geographically defined population (see comments)
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The contribution of low birth weight to severe vision loss in a geographically defined population (see comments)

机译：低出生体重对特定地区人口严重视力丧失的影响（见评论）

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AIMS: To describe the birthweight specific rate of severe vision loss among babies born between 1 January 1984 and 31 December 1987 to mothers resident in a geographically defined area, to classify the causes of vision loss by time of origin, and to describe the associated sensory and motor impairments and disabilities. METHODS: Cases were identified from a population register of children with early childhood impairment, which uses multiple sources of ascertainment. Further clinical information was retrieved from hospital records and by asking ophthalmologists caring for the children. RESULTS: 166 (1.25/1000 live births) children with severe vision loss diagnosed by the age of 5 years were identified. The rate among babies born weighing less than 1500 g at birth was 26 times higher than the rate for babies between 2500 g and 3499 g. These very low birthweight babies contribute 17.5% of all severely visually impaired children. Almost two thirds of children with severe vision loss have a lesion of prenatal origin. Other sensory or motor deficits are present in 69% of the children. Retinopathy of prematurity accounted for 5.4% of all visually impaired children and seven of the 166 children met the criteria for perinatal asphyxia. CONCLUSIONS: Although the contribution made by babies with a low birth weight to overall severe vision loss in the community is small, many of these children have additional impairments and probably place considerable demands on health and educational services and families. Reduction in the frequency of vision problems in the preschool population as a whole is unlikely to occur until there are major advances in the understanding of the aetiology and prevention of eye conditions of genetic, prenatal, and developmental origin.
机译：目的：描述1984年1月1日至1987年12月31日之间出生于地理区域的母亲的重度视力丧失的具体出生率，按起源时间分类视力丧失的原因，并描述相关的感觉以及运动障碍和残疾。方法：从儿童早期残疾儿童的人口登记册中确定病例，该登记册使用多种查明来源。进一步的临床信息可从医院记录中获取，也可以要求眼科医生照顾孩子。结果：确定了166名（1.25 / 1000活产婴儿）5岁以下被诊断为严重视力丧失的儿童。出生时体重小于1500 g的婴儿的比率是2500 g至3499 g的婴儿的比率的26倍。这些极低出生体重的婴儿占所有严重视力障碍儿童的17.5％。患有严重视力丧失的儿童中，近三分之二患有产前起源病变。 69％的儿童存在其他感觉或运动功能障碍。早产儿视网膜病变占所有视力障碍儿童的5.4％，166名儿童中有7名符合围产期窒息的标准。结论：尽管出生体重低的婴儿对社区整体严重视力丧失的贡献很小，但其中许多儿童还存在额外的障碍，可能对健康，教育服务和家庭提出了很高的要求。在学到病因学和预防遗传，产前和发育起源的眼疾方面取得重大进展之前，整个学龄前儿童的视力问题减少的可能性不大。

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