...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International journal of clinical pharmacology and therapeutics >Prescribing for migraine with the focus on selective 5HT1-receptor agonists: a pharmacy database analysis.
【24h】

Prescribing for migraine with the focus on selective 5HT1-receptor agonists: a pharmacy database analysis.

机译：开处方偏头痛的重点是选择性5HT1受体激动剂：药房数据库分析。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

OBJECTIVE: The primary aim was to determine the prescribing patterns and cost of drugs for migraine focusing on selective 5HT1-receptor agonists (triptans) in a primary care patient population. METHODS: A retrospective drug utilization consumption study was conducted. Data were obtained from a South African national private pharmacy group. The database consisted of all central nervous system prescriptions dispensed by the pharmacy group for 2008. RESULTS: A total of 22,102 patients (71.05% females) received 43,144 items for migraine a cost of R3,622,552 (average cost of R83.96 per item). The average age of patients was 44.90 (SD = 13.83) years, with 70.76% of patients between 30 and 59 years of age. A two-sample t-test assuming equal variances was conducted to compare prescribing to females and males. There was a significant difference. There were proportionally more females in the younger age groups and proportionately more males over 60 years. Patients were prescribed an average of 1.95 items for migraine over the year. The Lorenz curve was used to illustrate skewness in prescribing. Clonidine was the most frequently prescribed active ingredient (46.15%), followed by the combination of cyclizine, ergotamine and caffeine (29.62%). The agents for the prophylaxis of migraine (clonidine, flunarizine and pizotifen) accounted for 50.48% of prescribing frequency, but only 29.04% of cost. The triptans accounted for 18.94% of prescribing frequency and 53.54% of cost. Rizatriptan was the most frequently prescribed triptan. CONCLUSIONS: The findings were generally in agreement with other studies, but a lower prescribing rate for triptans was observed.
机译：目的：主要目的是确定偏头痛药物的处方模式和成本，重点是针对基层医疗患者群体中的选择性5HT1受体激动剂（曲普坦）。方法：进行回顾性药物利用消费研究。数据来自南非国家私人药房集团。该数据库由药房小组在2008年分配的所有中枢神经系统处方组成。结果：总共22,102名患者（71.05％女性）接受了43,144项偏头痛治疗，费用为R3,622,552（平均费用为R83.96）。 。患者的平均年龄为44.90（SD = 13.83）岁，其中30.59岁的患者为70.76％。进行了假设均等方差的两样本t检验，以比较男女处方药。有显着差异。在年轻年龄段中，女性成比例地增加，而60岁以上的男性成比例地增加。一年中，患者平均被偏头痛处方1.95项。洛伦兹曲线用于说明处方偏斜。可乐定是最常用的活性成分（46.15％），其次是环嗪，麦角胺和咖啡因的组合（29.62％）。预防偏头痛的药物（可乐定，氟那利嗪和吡唑替芬）占处方频率的50.48％，但仅占费用的29.04％。曲普坦占处方频率的18.94％和成本的53.54％。利扎曲普坦是最常用的曲普坦。结论：研究结果与其他研究基本一致，但曲坦类药物的处方率较低。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号