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首页> 外文期刊>International journal of clinical rheumatology. >Fatigue in rheumatic disease: an overview
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Fatigue in rheumatic disease: an overview

机译：风湿病的疲劳：概述

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摘要

Fatigue is a common and disabling symptom in a number of rheumatic diseases, including rheumatoid arthritis, ankylosing spondylitis and osteoarthritis. Patients frequently rank fatigue as one of their most disabling symptoms, adversely affecting quality of life and employment opportunities. The aims of this article are to: first, define the concept of fatigue in rheumatic disease, its nature, prevalence and impact-second, describe questionnaires that have been validated as measures of fatigue among people with rheumatic diseases; third, outline the factors which have been identified as influencing fatigue, including disease activity/severity, disability, pain, sleep disturbance, mood, self-efficacy, illness perceptions and coping; and finally, synthesize the sparse evidence currently available regarding the best strategies for managing fatigue in rheumatic disease. Recent research has suggested that disease-modifying antirheumatic drugs and biologic therapies are effective in ameliorating fatigue in both rheumatoid arthritis and ankylosing spondylitis, but the mechanism by which they reduce fatigue is not clear. Tailored exercise and psychological interventions show promise. Further studies are needed to determine the best ways of managing the fatigue associated with rheumatic disease. The assessment of fatigue in rheumatology clinics should be part of standard practice.
机译：疲劳是许多风湿性疾病的常见和致残症状，包括类风湿性关节炎，强直性脊柱炎和骨关节炎。患者经常将疲劳视为其最致残的症状之一，对生活质量和就业机会产生不利影响。本文的目的是：首先，定义风湿病中疲劳的概念，性质，患病率和影响;其次，描述已被验证为风湿病患者疲劳程度的问卷;第三，概述已确定影响疲劳的因素，包括疾病活动/严重程度，残疾，疼痛，睡眠障碍，情绪，自我效能，疾病知觉和应对方法;最后，综合目前有关控制风湿病疲劳最佳策略的稀疏证据。最近的研究表明，可改变疾病的抗风湿药和生物疗法可有效缓解类风湿性关节炎和强直性脊柱炎的疲劳，但减轻疲劳的机理尚不清楚。量身定制的运动和心理干预显示出希望。需要进一步的研究以确定治疗风湿病相关疲劳的最佳方法。风湿病诊所对疲劳的评估应成为标准做法的一部分。

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