Morphological and biochemical magnetic resonance techniques for cartilage imaging in rheumatoid arthritis: application and analysis

Goetz H Welsch; Siegfried Trattng; Nina Renner; Lars Lauer; Dominik Paul; Michael Uder

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Morphological and biochemical magnetic resonance techniques for cartilage imaging in rheumatoid arthritis: application and analysis

机译：类风湿关节炎软骨成像的形态学和生化磁共振技术：应用和分析

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This article focuses on high-field (3.0 Tesla) MRI in the visualization of the small joints of the finger in rheumatoid arthritis. High spatial resolution, based on optimized coil equipment and advanced sequence protocols can be achieved for morphological and biochemical imaging of small structures in small joints. Besides the structural degradation, as visualized by advanced high-resolution morphological MRI, biochemical changes in the structure of articular cartilage can be imaged. Early proteoglycan loss, as well as changes in the collagen matrix, can be quantified using delayed gadolinium-enhanced MRI of cartilage and T2 mapping. Hence, using an advanced morphological and biochemical magnetic resonance protocol, the pathophysiological pathway of rheumatoid arthritis might be elucidated, providing an objective and quantitative method to monitoring disease progression.

机译：本文重点介绍风湿性关节炎中手指小关节的可视化（3.0特斯拉）MRI。基于优化的线圈设备和先进的序列协议，可以实现高空间分辨率，从而对小关节中的小结构进行形态和生化成像。除了通过高级高分辨率形态MRI可视化的结构退化之外，还可以对关节软骨结构的生化变化进行成像。早期蛋白聚糖的丢失以及胶原蛋白基质的变化可以使用延迟的g增强MRI软骨和T2作图来定量。因此，使用先进的形态学和生化磁共振方案，可以阐明类风湿性关节炎的病理生理学途径，为监测疾病的进展提供一种客观和定量的方法。

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《International journal of clinical rheumatology.》 |2011年第1期|共13页
作者
Goetz H Welsch; Siegfried Trattng; Nina Renner; Lars Lauer; Dominik Paul; Michael Uder;
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正文语种 eng
中图分类全身性疾病;
关键词
articular cartilage; dGEMRIC; MRI; rheumatoid arthritis; T2 mapping;

机译：关节软骨dGEMRIC MRI风湿性关节炎T2定位;

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1. Morphological and biochemical magnetic resonance techniques for cartilage imaging in rheumatoid arthritis: application and analysis [J] . Goetz H Welsch, Siegfried Trattng, Nina Renner, International journal of clinical rheumatology. . 2011,第1期

机译：类风湿关节炎软骨成像的形态学和生化磁共振技术：应用和分析
2. Molecular imaging of cartilage damage of finger joints in early rheumatoid arthritis with delayed gadolinium-enhanced magnetic resonance imaging [J] . Arthritis and Rheumatism . 2012,第2期

机译：类风湿关节炎早期手指关节软骨损伤的分子影像学与延迟delayed增强磁共振成像
3. New techniques for cartilage magnetic resonance imaging relaxation time analysis: texture analysis of flattened cartilage and localized intra- and inter-subject comparisons. [J] . Carballido-Gamio J, Link TM, Majumdar S Magnetic resonance in medicine: official journal of the Society of Magnetic Resonance in Medicine . 2008,第6期

机译：软骨磁共振成像弛豫时间分析的新技术：扁平软骨的纹理分析以及局部对象间和对象间的比较。
4. Novel Automatic Tool for Magnetic Resonance Imaging Quantification of Bone Erosion Scoring in Rheumatoid Arthritis [C] . Patrizia Parascandolo, Lorenzo Cesario, Loris Vosilla, International conference on image analysis and processing;International workshop on recent advances in digital security: biometrics and forensics;Workshop on color in texture and material recognition;Workshop on medical imaging in rheumatology: advanced applications for the analysis of inflammation and damage in the rheumatoid joint;Workshop on image-based smart city application;International workshop on multimedia assisted dietary management;Workshop on scene background modeling and initalization;workshop on image and video processing for quality of multimedia experience . 2015

机译：类风湿关节炎的骨侵蚀得分的磁共振成像定量的新型自动工具
5. Quantitative musculoskeletal magnetic resonance imaging at 3.0T: Developing new techniques to detect morphological changes in human cartilage and bone in osteoarthritis and osteoporosis. [D] . Tameem, Hussain Zakiuddin. 2008

机译：3.0T时的定量肌肉骨骼磁共振成像：开发新技术以检测骨关节炎和骨质疏松症中人软骨和骨骼的形态变化。
6. New Techniques for Cartilage Magnetic Resonance Imaging Relaxation Time Analysis: Texture Analysis of Flattened Cartilage and Localized Intra- and Inter-subject Comparisons [O] . Julio Carballido-Gamio, Thomas M. Link, Sharmila Majumdar -1

机译：软骨磁共振成像弛豫时间分析的新技术：扁平软骨的纹理分析和局部对象间和对象间的比较
7. THU0619 THE VALUE OF MORPHOLOGICAL AND BIOCHEMICAL MAGNETIC RESONANCE IMAGING (MRI) OF RADIOCARPAL CARTILAGE FOR THE DIFFERENTIATION OF RHEUMATOID ARTHRITIS AND OSTEOARTHRITIS [O] . Philipp Sewerin, Lino Sawicki, Christoph Schleich, 2019

机译：radiocarpal软骨形态学和生化磁共振成像（MRI）的价值，用于分化类风湿性关节炎和骨关节炎

Morphological and biochemical magnetic resonance techniques for cartilage imaging in rheumatoid arthritis: application and analysis

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