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Cognitive disorders and brain MRI correlations in primary Sjogrens syndrome: unlocking the secret of cognitive symptoms

机译:原发性干燥综合征的认知障碍和脑MRI相关性:揭示认知症状的秘密

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摘要

Little is known concerning the mechanisms of cognitive impairment in primary Sjogren's syndrome. However, recent technological advances have made detailed brain imaging studies possible, which have the potential to estimate more precisely the prevalence of CNS lesions in primary Sjogren's syndrome and to provide information on the severity and mechanisms of CNS tissue damage. Novel neuroimaging protocols can provide a window into cerebral organization that is not accessible with conventional imaging methods. Investigation of cognitive function with state of the art high-resolution structural and functional brain MRI could illuminate the mechanisms contributing to subtle cognitive dysfunction and guide the development of specific therapeutic approaches.
机译:关于原发性干燥综合征的认知障碍机制知之甚少。然而,最近的技术进步使详细的脑部成像研究成为可能,这有可能更准确地估计原发性干燥综合征中CNS病变的发生率,并提供有关CNS组织损伤的严重程度和机制的信息。新型的神经影像学协议可以提供通向传统成像方法无法访问的大脑组织的窗口。用最先进的高分辨率结构和功能性脑MRI对认知功能进行研究可以阐明导致细微认知功能障碍的机制,并指导特定治疗方法的发展。

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