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首页> 外文期刊>International journal of clinical rheumatology. >Comparison of the Genant-modified Sharp and van der Heijde-modified Sharp scoring methods for radiographic assessment in rheumatoid arthritis
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Comparison of the Genant-modified Sharp and van der Heijde-modified Sharp scoring methods for radiographic assessment in rheumatoid arthritis

机译：类风湿性关节炎放射线评估的Genant修饰的Sharp和Van der Heijde修饰的Sharp评分方法的比较

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Objectives: To compare the Genant-modified Sharp and van der Heijde-modified Sharp composite scoring methods for evaluating radiographs of the hands, wrists and feet in patients with rheumatoid arthritis. Materials & methods: Standardized radiographs of the hands, wrists and feet of 28 patients with established rheumatoid arthritis taken 1 year apart were scored independently with each of the two methods by two radiologists blinded to each other's scores. One of the radiologists also re-read each case with each method to determine intrareader agreement. The smallest detectable change (SDC), normalized to the range of scores observed with each method, and the intra- and inter-reader reproducibilities expressed as intraclass correlation coefficients, were determined for each method. Results: The Genant-Sharp scores and van der Heijde-Sharp scores correlated strongly with each other (r~2 ranged from 0.95 to 0.99) and demonstrated high intra- and inter-reader agreement (intraclass correlation coefficients ranged from 0.84 to 0.98). The Genant-Sharp method demonstrated smaller normalized SDCs (4.7-7.9) than did the van der Heijde-Sharp method (6.4-10.5), but the difference was not statistically significant except for the joint space narrowing score read by the single radiologist. Furthermore, the proportion of patients showing change greater than 0 or greater than SDC were not significantly different between the two methods. Conclusion: The Genant-Sharp and van der Heijde-Sharp methods demonstrated relatively similar performances for scoring erosion and joint space narrowing in the hands, wrists and feet.
机译：目的：比较Genant改良的Sharp和Van der Heijde改良的Sharp复合评分方法，评估类风湿关节炎患者手，腕和足的X光片。材料与方法：两位放射线医师对彼此不计分的分数，分别对间隔1年拍摄的28例类风湿性关节炎患者的手，腕和足进行了标准化的X线照片，分别对这两种方法进行了评分。一位放射科医生还用每种方法重新阅读了每种情况，以确定阅读器内的一致性。确定每种方法的最小可检测变化（SDC），将其标准化为每种方法所观察到的分数范围，并以类内相关系数表示阅读器内和阅读器间的可重复性。结果：Genant-Sharp评分和van der Heijde-Sharp评分之间具有很强的相关性（r〜2在0.95至0.99之间），并显示出较高的读者内和读者间一致性（类内相关系数在0.84至0.98之间）。 Genant-Sharp方法显示的标准化SDC（4.7-7.9）比van der Heijde-Sharp方法（6.4-10.5）小，但差异没有统计学意义，除了单个放射线医师读取的关节间隙变窄评分。此外，两种方法显示变化大于0或大于SDC的患者比例没有显着差异。结论：Genant-Sharp和van der Heijde-Sharp方法在得分侵蚀和手，腕和脚关节间隙狭窄方面表现出相对相似的性能。

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