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The incidence of preterm deliveries decreases in Finland.

机译:早产的发生率在芬兰有所下降。

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OBJECTIVE; We examined the trends and risk factors of preterm delivery. DESIGN: Register-based retrospective cohort study from Finland. SETTING: National Medical Birth Register data during 1987-2005. POPULATION: The study population consisted of 1 137 515 deliveries, of which 59 025 were preterm (5.2%). METHODS: We calculated the population attributable risks for using the risk factor prevalence rates in the population. We further calculated odds ratios with 95% CI by multivariate logistic regression to adjust for confounders. MAIN OUTCOME MEASURES: Preterm delivery rate subclassified into moderately preterm (32-36 weeks), very preterm (28-31 weeks) and extremely preterm (less than 28 weeks). RESULTS; Preterm delivery rates increased from 5.1% in the late 1980s to 5.4% in the late 1990s but then decreased to 5.2% for 2001-05. The proportion of extremely preterm deliveries decreased substantially by 12% (P < 0.01). The greatest risk factors were multiplicity (OR 13.72, 95% CI 13.26-14.19), followed by elective delivery (OR 1.86, 95% CI 1.82-1.89), primiparity (OR 1.47, 95% CI 1.45-1.50), in vitro fertilisation treatment (OR 1.39, 95% CI 1.31-1.47), maternal smoking (OR 1.31, 95% CI 1.29-1.34) and advanced maternal age (OR 1.02, 95% CI 1.02-1.03 for each additional year of age). Prematurity rates decreased by 1.8% after adjusting for risk variables. CONCLUSIONS: The rate of preterm delivery has not increased from 1987 to 2005 in Finland, while the risk for extremely preterm delivery has decreased. This finding is in contrast with recent trends in other countries.
机译:目的;我们检查了早产的趋势和风险因素。设计:来自芬兰的基于登记的回顾性队列研究。地点:1987-2005年国家医疗出生登记数据。人口:研究人群包括1 137 515例分娩,其中59 025例为早产(5.2%)。方法:我们使用人群中的危险因素患病率计算了人群可归因的风险。我们通过多元logistic回归进一步计算混杂系数为95%的优势比。主要观察指标:早产率分为中度早产(32-36周),早产(28-31周)和极早(少于28周)。结果;早产率从1980年代后期的5.1%上升到1990年代后期的5.4%,但随后下降到2001-05年度的5.2%。极早产的比例大幅下降了12%(P <0.01)。最大的危险因素是多重性(OR 13.72,95%CI 13.26-14.19),其次是选择性分娩(OR 1.86,95%CI 1.82-1.89),初产(OR 1.47,95%CI 1.45-1.50),体外受精治疗(OR 1.39,95%CI 1.31-1.47),孕妇吸烟(OR 1.31,95%CI 1.29-1.34)和高龄产妇年龄(OR 1.02,每增加1岁年龄组95%CI 1.02-1.03)。调整风险变量后,早产率下降了1.8%。结论:从1987年到2005年,芬兰早产率没有增加,而极端早产的风险有所降低。这一发现与其他国家的最新趋势形成鲜明对比。

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