...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>International journal of gynecological cancer: official journal of the International Gynecological Cancer Society >Which surgical procedure for patients with atypical endometrial hyperplasia?
【24h】

Which surgical procedure for patients with atypical endometrial hyperplasia?

机译：非典型子宫内膜增生患者应采用哪种手术方法？

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

OBJECTIVE: To determine the occult coexistence of endometrial carcinoma in patients with atypical endometrial hyperplasia and to compare histological prognostic factors according to lymph node status in occult endometrial carcinoma. MATERIALS AND METHODS: Two hundred and four patients from two referral centers (during the period 1990-2003) who were operated on within 1 month of endometrial biopsy for symptomatic endometrial hyperplasia without receiving any medical treatment were included retrospectively. Patients having preoperative endometrial biopsy results of concomitant endometrial hyperplasia and carcinoma were excluded from the study. Fifty-six patients having atypia in preoperative biopsy (group I) were compared with 148 patients without atypia (group II). Chi-square and Mann-Whitney U-tests were used for statistical analyses. RESULTS: No significant difference was observed between the two groups according to age or menopausal status. Patients in group II had significantly higher parity than patients in group I. In group I, 62.5% of the patients had endometrial carcinoma, 21.4% had endometrial hyperplasia, and 16.1% had normal endometrium in hysterectomy specimens. In group II, the percentages were 5.4, 38.5, and 56.1%, respectively. Complete surgical staging was performed in 20 patients. Four patients had metastatic lymph nodes. All of them had grade 2 tumors with lymphovascular space involvement. Three of them had nonendometrioid tumors. CONCLUSION: Careful intraoperative and preoperative evaluation of the endometrium must be the sine qua non for patients with atypical endometrial hyperplasia. It is reasonable to do frozen section at the time of hysterectomy for atypical endometrial hyperplasia, and if grade 2/3 of nonendometrioid cancer with lymphovascular space involvement is found, complete surgical staging should be performed.
机译：目的：确定非典型子宫内膜增生患者子宫内膜癌的隐匿性共存，并根据隐匿性子宫内膜癌的淋巴结状态比较组织学预后因素。材料与方法：回顾性分析了来自两个转诊中心（1990年至2003年）的240例因子宫内膜活检而在1个月内因症状性子宫内膜增生而接受手术治疗的患者。具有术前子宫内膜活检结果并发子宫内膜增生和癌的患者被排除在研究之外。将56例术前有异型的患者（I组）与148例无异型的患者（II组）进行了比较。卡方检验和Mann-Whitney U检验用于统计分析。结果：根据年龄或绝经状态，两组之间没有显着差异。 II组患者的均价明显高于I组。在I组中，子宫切除术标本中62.5％的患者患有子宫内膜癌，21.4％的患者子宫内膜增生，16.1％的子宫内膜正常。在第二组中，该百分比分别为5.4％，38.5％和56.1％。对20例患者进行了完整的手术分期。 4例患者有转移性淋巴结转移。他们全部患有2级肿瘤，并伴有淋巴血管间隙。其中三个患有非子宫内膜样肿瘤。结论：对于非典型子宫内膜增生患者，必须对子宫内膜进行术中和术前的仔细评估。对于非典型子宫内膜增生，在子宫切除术时进行冰冻切片是合理的，并且如果发现2/3级非子宫内膜样癌伴有淋巴血管间隙受累，则应进行完整的手术分期。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号