...
首页> 外文期刊>International journal of immunogenetics >Discovery of HLA-B*480102 in Taiwanese.
【24h】

Discovery of HLA-B*480102 in Taiwanese.

机译:在台湾发现HLA-B * 480102。

获取原文
获取原文并翻译 | 示例
           

摘要

Summary :Human leucocyte antigen (HLA)-B48, an antigen within 7C CREG (cross-reacting group) (Steiner et al, 2001) that cross-reacts frequently with HLA-B40 (i.e. HLA-B60 and -B61) group of antibodies serologically, can be found in Alaskan Natives (Leffell et al., 2002), Amerindians (Martinez-Naves et al., 1997), African Americans, Caucasians, and Oriental ethnicities (Mori et al., 1997; Schipper et al, 1997; Cao etal, 2001; Middleton etal, 2004; Hong et al, 2005; Itoh et al, 2005; Lee et al, 2005; Ogata et al, 2007), Sequencing investigations demonstrated that the common allele encoding the B48 antigen is B*4801 (Belich et al, 1992). To date, there are at least 16 WHO recognized B*48 alleles according to the most recent report from the WHO nomenclature committee (Marsh etal, 2005), Here we report a newly discovered allele BM80102, a variant of B*4801, detected in a 55-year-old Taiwanese patient of Minan origin (southern China).
机译:摘要:人白细胞抗原(HLA)-B48,在7C CREG(交叉反应基团)中的抗原(Steiner等,2001),经常与HLA-B40(即HLA-B60和-B61)抗体组交叉反应在血清学上,可以在阿拉斯加土著人(Leffell等人,2002),美洲印第安人(Martinez-Naves等人,1997),非裔美国人,白种人和东方人种中找到(Mori等人,1997; Schipper等人,1997)。 ; Cao等,2001; Middleton等,2004; Hong等,2005; Itoh等,2005; Lee等,2005; Ogata等,2007),测序研究表明,编码B48抗原的常见等位基因是B *。 4801(Belich等,1992)。迄今为止,根据WHO命名委员会的最新报告(Marsh等人,2005年),至少有16个WHO公认的B * 48等位基因。在这里,我们报道了新发现的等位基因BM80102,它是B * 4801的变异体,在一名55岁的台湾裔Minan籍台湾患者(中国南方)。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号