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首页> 外文期刊>International journal of geriatric psychiatry >Fifteen year comparison of antipsychotic use in people with dementia within hospital and nursing home settings: sequential cross-sectional study.
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Fifteen year comparison of antipsychotic use in people with dementia within hospital and nursing home settings: sequential cross-sectional study.

机译：在医院和疗养院环境中对痴呆症患者使用抗精神病药物的15年比较：连续横断面研究。

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OBJECTIVE: The use of antipsychotics to treat people with behavioural and psychological symptoms associated with dementia is controversial, especially in long-stay settings. We assessed the relationship between behaviour, function and antipsychotic use in people with dementia in a long-stay psychiatric unit and designated elderly mentally ill (EMI) nursing homes over a 15-year period. METHOD: Sequential cross-sectional studies assessing twelve behaviours and seven measures of function for each patient. Antipsychotic and antidepressant use was obtained from current prescription records. RESULTS: Regular antipsychotic use in hospital fell between 1990 and 1998. In 1998 use in nursing homes was significantly greater than in hospital, and increased between 1998 and 2005. Noisiness/verbal aggression (NVA) was the only behaviour more commonly associated with regular antipsychotic use over that timescale. Those with low levels of core symptoms (p = 0.021) and high dependency patients (p = 0.001) were more likely to be receiving regular antipsychotics in nursing homes than in hospital. Depression was not treated well even when identified. CONCLUSION: Compared to a long-stay hospital setting, antipsychotic drug use for people with dementia in nursing homes has risen and become less systematic. This cannot be explained by increasing core behaviour symptoms or differences in physical dependency.
机译：目的：使用抗精神病药治疗患有与痴呆相关的行为和心理症状的人是有争议的，尤其是在长期住院的情况下。我们评估了长期住院的精神病科和指定的老年精神病（EMI）疗养院中痴呆症患者的行为，功能和抗精神病药物使用之间的关系，为期15年。方法：按顺序进行横断面研究，评估每位患者的十二种行为和七种功能指标。从当前处方记录中获得了抗精神病药和抗抑郁药的使用。结果：1990年至1998年间，医院常规抗精神病药物使用量下降。1998年，疗养院中常规抗精神病药物的使用量显着高于医院，1998年至2005年间，抗精神病药物的使用量有所增加。在该时间范围内使用。核心症状水平较低（p = 0.021）和高依赖性患者（p = 0.001）的人比在医院接受定期抗精神病药治疗的可能性更高。抑郁症即使被发现也没有得到很好的治疗。结论：与长期住院的医院相比，在疗养院中用于痴呆症患者的抗精神病药物的使用有所增加，而且系统性较差。这不能通过增加核心行为症状或身体依赖性差异来解释。

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