首页> 外文期刊>International journal of laboratory hematology >Can automated blood film analysis replace the manual differential? An evaluation of the CellaVision DM96 automated image analysis system.
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Can automated blood film analysis replace the manual differential? An evaluation of the CellaVision DM96 automated image analysis system.

机译:自动血膜分析可以代替手动差异吗?对CellaVision DM96自动化图像分析系统的评估。

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摘要

Automation of differentials is desirable for economic and time-saving reasons. Over the last 20 years, automated imaging processes have started to be introduced where stained blood films are scanned by a computer-driven microscope and leucocytes classified; however, early methods were slow and had difficulty in classifying abnormal cells. More recently the CellaVisiontrade mark DM96 (CellaVision AB, Lund, Sweden) has been introduced with added features such as continuous loading of slides and a faster throughput than previous instruments. The accuracy of CellaVision(TM) DM96 has been evaluated by comparing results to reference manual differentials. Results from different operators using the DM96 were compared with their own manual differential and to a 400-cell reference manual differential. Precision of the instrument was compared to the manual differential. The preclassification accuracy of the DM96 was 89.2%. Precision was similar to that of the 100-cell manual differential. The DM96 was faster thanthe manual method, even after reclassification by a laboratory scientist of any cells wrongly categorized by the instrument. The DM96 accuracy in morphological classification of leucocytes and red blood cells; depends upon both blood pathology and experience of the laboratory scientist using the instrument. For some cell types and operators, DM96 accuracy was better than the individual's 100 cell manual differential.
机译:出于经济和省时的原因,希望差速器自动化。在过去的20年中,已经开始引入自动成像过程,其中通过计算机驱动的显微镜对染色的血膜进行扫描,并对白细胞进行分类。然而,早期方法缓慢且难以对异常细胞进行分类。最近,引入了CellaVisiontrade商标DM96(CellaVision AB,瑞典隆德),具有附加功能,例如连续加载载玻片和比以前的仪器更快的通量。通过将结果与参考手动差速器进行比较,评估了CellaVision™DM96的准确性。将使用DM96的不同操作员的结果与他们自己的手动差速器和400单元参考手动差速器进行比较。将仪器的精度与手动差速器进行了比较。 DM96的预分类精度为89.2%。精度类似于100芯手动差速器。 DM96的速度比手动方法快,甚至在实验室科学家对仪器错误分类的任何细胞进行重新分类之后也是如此。 DM96在白细胞和红细胞形态分类中的准确性;取决于血液病理和实验室科学家使用仪器的经验。对于某些电池类型和操作员,DM96的精度优于个人的100电池手动差速器。

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