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首页> 外文期刊>International journal of laboratory hematology >Performance evaluation of the abbott CELL-DYN emerald for use as a bench-top analyzer in a research setting
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Performance evaluation of the abbott CELL-DYN emerald for use as a bench-top analyzer in a research setting

机译:研究环境中用作台式分析仪的abbott CELL-DYN祖母绿的性能评估

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Introduction: The CELL-DYN Emerald is a compact bench-top hematology analyzer that can be used for a three-part white cell differential analysis. To determine its utility for analysis of human and mouse samples, we evaluated this machine against the larger CELL-DYN Sapphire and Sysmex XT2000iV hematology analyzers. Methods: 120 human (normal and abnormal) and 30 mouse (normal and abnormal) samples were analyzed on both the CELL-DYN Emerald and CELL-DYN Sapphire or Sysmex XT2000iV analyzers. For mouse samples, the CELL-DYN Emerald analyzer required manual recalibration based on the histogram populations. Results: Analysis of the CELL-DYN Emerald showed excellent precision, within accepted ranges (white cell count CV% = 2.09%; hemoglobin CV% = 1.68%; platelets CV% = 4.13%). Linearity was excellent (R2 ≥ 0.99), carryover was minimal (1%), and overall interinstrument agreement was acceptable for both human and mouse samples. Comparison between the CELL-DYN Emerald and Sapphire analyzers for human samples or Sysmex XT2000iV analyzer for mouse samples showed excellent correlation for all parameters. Conclusion: The CELL-DYN Emerald was generally comparable to the larger reference analyzer for both human and mouse samples. It would be suitable for use in satellite research laboratories or as a backup system in larger laboratories.
机译:简介:CELL-DYN Emerald是一款紧凑型台式血液分析仪,可用于三部分式白细胞差异分析。为了确定其用于分析人类和小鼠样品的效用,我们针对大型CELL-DYN蓝宝石和Sysmex XT2000iV血液学分析仪对该机器进行了评估。方法:在CELL-DYN绿宝石和CELL-DYN蓝宝石或Sysmex XT2000iV分析仪上分析了120个人(正常和异常)和30小鼠(正常和异常)样品。对于小鼠样品,CELL-DYN翡翠分析仪需要根据直方图种群进行手动重新校准。结果:在可接受的范围内(白细胞计数CV%= 2.09%;血红蛋白CV%= 1.68%;血小板CV%= 4.13%),CELL-DYN祖母绿的分析显示出极好的精度。线性极好(R2≥0.99),残留极小(<1%),并且整体的仪器一致性对于人和小鼠样品都是可以接受的。 CELL-DYN翡翠和蓝宝石分析仪(用于人类样品)或Sysmex XT2000iV分析仪(用于小鼠样品)之间的比较表明,所有参数均具有极好的相关性。结论:对于人和小鼠样品,CELL-DYN祖母绿通常可与较大的参考分析仪相媲美。它适用于卫星研究实验室或大型实验室的备用系统。

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