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首页> 外文期刊>International journal of molecular imaging >SPECT Imaging of Epilepsy: An Overview and Comparison with F-18 FDG PET
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SPECT Imaging of Epilepsy: An Overview and Comparison with F-18 FDG PET

机译：癫痫的SPECT成像：与F-18 FDG PET的概述和比较

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摘要

Epilepsy surgery is highly effective in treating refractory epilepsy, but requires accurate presurgical localization of the epileptogenic focus. Briefly, localization of the region of seizure onset traditionally dependents on seizure semiology, scalp EEG recordings and correlation with anatomical imaging modalities such as MRI. The introduction of noninvasive functional neuroimaging methods, including single-photon emission computed tomography (SPECT) and positron emission tomography (PET) has dramatically changed the method for presurgical epilepsy evaluation. These imaging modalities have become powerful tools for the investigation of brain function and are an essential part of the evaluation of epileptic patients. Of these methods, SPECT has the practical capacity to image blood flow functional changes that occur during seizures in the routine clinical setting. In this review we present the basic principles of epilepsy SPECT and PET imaging. We discuss the properties of the SPECT tracers to be used for this purpose and imaging acquisition protocols as well as the diagnostic performance of SPECT in addition to SPECT image analysis methods. This is followed by a discussion and comparison to F-18 FDG PET acquisition and imaging analysis methods.
机译：癫痫手术在治疗难治性癫痫中非常有效，但是需要精确的术前定位来确定癫痫病灶。简而言之，癫痫发作区域的定位传统上取决于癫痫发作的符号学，头皮脑电图记录以及与诸如MRI的解剖学成像方式的相关性。非侵入性功能性神经影像学方法的引入，包括单光子发射计算机断层扫描（SPECT）和正电子发射断层扫描（PET），极大地改变了术前癫痫评估方法。这些成像方式已成为研究脑功能的强大工具，并且是评估癫痫患者的重要组成部分。在这些方法中，SPECT具有对常规临床环境中癫痫发作期间发生的血流功能变化进行成像的实用能力。在这篇综述中，我们介绍了癫痫的SPECT和PET成像的基本原理。除了SPECT图像分析方法外，我们还将讨论用于此目的的SPECT示踪剂的性质和成像采集协议，以及SPECT的诊断性能。接下来是对F-18 FDG PET采集和成像分析方法的讨论和比较。

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