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首页> 外文期刊>British Journal of Radiology >Pancreatic ductal adenocarcinoma with intratumoral cystic lesions on MRI: correlation with histopathological findings.
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Pancreatic ductal adenocarcinoma with intratumoral cystic lesions on MRI: correlation with histopathological findings.

机译：胰管腺癌伴肿瘤内囊性病变的MRI：与组织病理学发现的相关性。

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The purpose of this study was to evaluate intratumoral cystic lesions of pancreatic ductal adenocarcinoma (PDAC) depicted on MRI, and to correlate these cystic lesions with their histopathological findings. This study included 12 patients (7 males and 5 females; mean age, 59 years) with intratumoral cystic lesions of PDAC detected on a retrospective MRI review. We reviewed the histopathological findings of the cystic lesions within PDACs and analysed the MRI findings, focusing on the appearance of the intratumoral cystic lesions, i.e. the size, number, margin and intratumoral location, and on the ancillary findings of PDAC, i.e. peripancreatic infiltration, upstream pancreatic duct dilatation and distal parenchymal atrophy. Intratumoral cystic lesions were classified as neoplastic mucin cysts (n = 7, 58%) or cystic necrosis (n = 5, 42%) according to the histopathological findings; they ranged in greatest dimension from 0.5 cm to 3.4 cm (mean, 1.7 cm). Seven patients had only one cystic lesion each, while the remaining five had multiple cystic lesions. Most of the neoplastic mucin cysts had smooth margins (n = 6, 86%) and eccentric locations (n = 6), whereas most cystic necroses had irregular margins (n = 4, 80%) and centric locations (n = 4). The most common ancillary findings of PDAC were peripancreatic infiltration, distal pancreatic atrophy and upstream pancreatic duct dilatation (92%, 75% and 58%, respectively). The intratumoral cystic lesions of PDACs on MRI were classified as either neoplastic mucin cysts with smooth margins and eccentric locations or cystic necroses with irregular margins and centric locations.
机译：这项研究的目的是评估MRI描绘的胰腺导管腺癌（PDAC）的瘤内囊性病变，并将这些囊性病变与其组织病理学发现相关联。这项研究包括12例患者（7例男性和5例女性;平均年龄59岁），他们在回顾性MRI检查中发现了PDAC的肿瘤内囊性病变。我们回顾了PDAC内囊性病变的组织病理学发现，并分析了MRI表现，重点是肿瘤内囊性病变的外观，即大小，数量，边缘和肿瘤内位置，以及PDAC的辅助发现，即胰周浸润，上游胰管扩张和远端实质性萎缩。根据组织病理学发现，瘤内囊性病变分为肿瘤性粘蛋白囊肿（n = 7，58％）或囊性坏死（n = 5，42％）。它们的最大尺寸范围从0.5厘米到3.4厘米（平均1.7厘米）。七名患者每人只有一个囊性病变，而其余五人有多个囊性病变。大多数肿瘤性粘蛋白囊肿边缘光滑（n = 6，86％）和偏心位置（n = 6），而大多数囊性坏死囊边缘不规则（n = 4，80％）和中心位置（n = 4）。 PDAC最常见的辅助检查结果是胰周浸润，远端胰腺萎缩和上游胰管扩张（分别为92％，75％和58％）。 MRI上PDAC的肿瘤内囊性病变被分类为边缘光滑且偏心的肿瘤性黏液囊肿或边缘和中心不规则的囊性坏死。

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