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首页> 外文期刊>American journal of medical genetics, Part A >Hyperamylasemia/hyperlipasemia in a child with propionic acidemia.
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Hyperamylasemia/hyperlipasemia in a child with propionic acidemia.

机译:丙酸血症儿童的高淀粉血症/高脂血症。

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Acute pancreatitis is relatively uncommon in children, often seen as a result of trauma, obstruction, systemic disorders, and drugs; a large number are deemed idiopathic. An increasingly reported predisposing group of conditions are the organic acidemias with 8% of effected children in one study developing pancreatitis [Clarke et al., 1994]. Pancreatitis has been described complicating meth-ylmalonic acidemia, isovaleric acidemia, maple syrup urine disease, glutaric acidemia type I, glutaric acidemia type II, and propionic acidemia [Burlina et al., 1995; Kahler et al., 1996; Lemire et al., 1996; Coskun et al., 1997]. Pancreatitis in these children may be difficult to diagnose due to the similarity of symptoms in acute pancreatitis and metabolic crises due to the organic acidemias [Coskun et al., 1997]. Also, amylase and lipase levels are not often included during laboratory testing and elevation in these enzymes alone does not confirm pancreatitis.
机译:儿童急性胰腺炎相对少见,通常是由于外伤,阻塞,全身性疾病和药物引起的;大量被认为是特发性的。在一项发展为胰腺炎的研究中,越来越多的易患病症是有机酸血症,其中8%的患儿患有胰腺炎[Clarke et al。,1994]。已经描述了胰腺炎并发甲基化丙二酸血症,异戊酸血症,枫糖浆尿病,I型戊二酸血症,II型戊二酸血症和丙酸血症[Burlina et al。,1995;卡勒(Kahler)等人,1996; Lemire et al。,1996。 Coskun et al。,1997]。这些儿童的胰腺炎可能由于急性胰腺炎的症状相似和有机酸血症引起的代谢危机而难以诊断[Coskun et al。,1997]。同样,在实验室测试期间,淀粉酶和脂肪酶的水平通常不包括在内,仅这些酶的升高就不能确认胰腺炎。

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