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首页> 外文期刊>British journal of neurosurgery >Stereotactic brain biopsy: An audit of sampling reliability in a clinical case series.
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Stereotactic brain biopsy: An audit of sampling reliability in a clinical case series.

机译：立体定向脑活检：对临床病例系列中抽样可靠性的审核。

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Stereotactic brain biopsy is the current gold standard procedure to obtain a neuropathological diagnosis. An audit of 207 stereotactic cases, between January 1997 and December 2000 was carried out. The aim was to determine the optimum number of target sites required to make the final diagnosis and thereby set up recommendations for future practice. The overall diagnostic success rate was 89.3%. A significant positive correlation between the number of targets taken and the probability of achieving the final diagnosis was seen. In a subset of glioblastoma cases 96.1% of the tumours could have been confidently diagnosed on the basis of any two of the targets chosen, although often more targets were taken than this. The recommendations made by the audit were: (i) in cases where it is suspected the lesion does not require grading, one target site should be taken and further sites should only be taken if the first proves to be non diagnostic; (ii) in suspected glial series tumours, two targets should be routinely taken, with further sites taken only if these prove inconclusive on intraoperative smear.
机译：立体定向脑活检是目前获得神经病理学诊断的金标准程序。在1997年1月至2000年12月期间，对207个立体定向病例进行了审计。目的是确定进行最终诊断所需的最佳靶位点数量，从而为将来的实践提出建议。总体诊断成功率为89.3％。观察到的目标数量与最终诊断的可能性之间存在显着的正相关。在成胶质细胞瘤病例的子集中，根据所选择的任何两个靶标，可以确定地诊断出96.1％的肿瘤，尽管通常采取的靶标多于此。审计所提出的建议是：（i）如果怀疑病灶不需要分级，则应选择一个目标部位，并且只有在第一个被证实不能诊断的情况下才应采取其他部位; （ii）在可疑的神经胶质系列肿瘤中，应常规采取两个靶点，只有在术中涂片结果尚无定论时才采取进一步的靶点。

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