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Effects of resistance training on cytokines.

机译:抵抗训练对细胞因子的影响。

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It is speculated that exercise training decreases resting levels of tumor necrosis factor alpha (TNF-alpha) and C-reactive protein (CRP); reduces body mass and leptin (LP); and increases adiponectin (AD) and insulin sensitivity. This systematic review analyzed the effectiveness of resistance training (RT) longitudinal clinical studies on AD, LP, CRP and TNF-alpha. Seventeen studies were included and the majority of randomized controlled trials support that RT produces increases in AD, and decreases in both LP and CRP. Greater responses in AD and LP were evident in overweight and obese individuals; while RT appeared to be effective in reducing CRP in obese individuals, and older adults. Additionally, women may be more responsive to RT effects on AD, LP and CRP. Training duration and intensity may affect the response of AD and CRP with greater responses shown with 16 weeks or more of training and/or with intensities greater than 80% of one repetition maximum. No response to RT of TNF-alpha levels was apparent. Although based on a limited number of studies, some of which are uncontrolled non-randomized in design, our review suggests some positive effects of RT programs on cytokine levels, but specifics of the responses in different populations need further elucidation.
机译:据推测,运动训练可降低肿瘤坏死因子α(TNF-α)和C反应蛋白(CRP)的静息水平;减少体重和瘦素(LP);并增加脂联素(AD)和胰岛素敏感性。该系统评价分析了针对AD,LP,CRP和TNF-alpha的抵抗训练(RT)纵向临床研究的有效性。纳入了十七项研究,大多数随机对照试验支持RT导致AD升高,LP和CRP降低。超重和肥胖个体对AD和LP的反应明显。而RT似乎可以有效降低肥胖者和老年人的CRP。此外,女性可能对RT对AD,LP和CRP的反应更敏感。训练持续时间和强度可能会影响AD和CRP的反应,在16周或更长时间的训练中和/或强度大于一个重复最大值的80%时,会显示出更大的响应。对TNF-α水平的RT没有反应是明显的。尽管基于有限的研究,其中一些是不受控制的非随机设计,但我们的综述表明RT程序对细胞因子水平具有一定的积极影响,但是不同人群中反应的具体情况还需要进一步阐明。

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