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A mobile DNP polarizer for clinical applications

机译:用于临床应用的移动DNP偏振器

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摘要

A mobile and low-cost apparatus for dynamic nuclear polarization (DNP) hyperpolarization based on a Halbach magnet is presented and its performance is demonstrated at room temperature and with three different radical species dissolved in a glycerol-water mixture. DNP enhancement factors for a triarylmethyl-based radical, TEMPOL and a polyelectrolyte spin-labeled with nitroxide radicals are measured as a function of the microwave power, and the extrapolated maximum enhancement factors are compared. The spin-labeled polyelectrolyte shows the best DNP efficiency and H-1 DNP enhancement factors up to -50 were observed and a maximum enhancement factor of -80 was projected. The results demonstrate that with the new mobile apparatus reliable DNP experiments can be performed with reasonably high H-1-DNP enhancements.
机译:提出了一种基于Halbach磁体的动态低成本低成本用于动态核极化(DNP)超极化的设备,并在室温下以及将三种不同的自由基物质溶解在甘油-水混合物中的情况下证明了其性能。测量了基于三芳基甲基的自由基TEMPOL和自旋标记有氮氧化物自由基的聚电解质的DNP增强因子,它是微波功率的函数,并比较了外推的最大增强因子。自旋标记的聚电解质显示出最佳的DNP效率,观察到的H-1 DNP增强因子最高为-50,最大增强因子为-80。结果表明,使用新的移动设备,可以在合理的H-1-DNP增强下执行可靠的DNP实验。

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