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Two-dimensional NMR relaxation study of the pore structure in silicone hydrogel contact lenses

机译:硅胶水凝胶隐形眼镜孔结构的二维NMR弛豫研究

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摘要

A combination of two-dimensional nuclear magnetic resonance (NMR) proton relaxometry and differential interference contrast optical microscopy is used to compare the pore structures of hydroxyethyl methacrylate-based hydrogels used in conventional contact lenses with three silicone hydrogels primarily developed for continuous-wear contact lenses. It is shown that both types of hydrogel have a connected network of nanopores but that, in addition, the silicone hydrogels contain pores on the micrometer scale that enhances their permeability. The potential of other two-dimensional NMR relaxation and diffusion methods for detailed characterization of hydrogels is discussed.
机译:结合使用二维核磁共振(NMR)质子弛豫法和微分干涉对比光学显微镜来比较传统隐形眼镜中使用的甲基丙烯酸羟乙酯基水凝胶的孔结构与主要为连续佩戴隐形眼镜开发的三种有机硅水凝胶。结果表明,两种类型的水凝胶都具有相连的纳米孔网络,但此外,硅酮水凝胶包含微米级的孔,可增强其渗透性。讨论了其他二维NMR弛豫和扩散方法对水凝胶进行详细表征的潜力。

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