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首页> 外文期刊>British journal of neurosurgery >Evaluation of posttraumatic vasospasm, hyperaemia, and autoregulation by transcranial colour-coded duplex sonography.
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Evaluation of posttraumatic vasospasm, hyperaemia, and autoregulation by transcranial colour-coded duplex sonography.

机译：经颅彩色编码双工超声检查评估创伤后血管痉挛，充血和自动调节。

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摘要

Serial transcranial colour-coded duplex sonography (TCCS) was performed on 24 adult patients with severe head injury (GCS 8 or less). Flow velocities were obtained from the middle cerebral artery (MCA) and extracranial internal carotid artery (EICA). An autoregulation study was done using the transient hyperaemic response test, evidence of vasospasm (V-MCA greater than 100 cm/s and Lindegaard ratio more than 3) was found in nine patients (37%). Two of these developed non-contusion-related infarction and two others contusion-related infarction. This was significant (p < 0.05). Vasospasm started around day 2, reaching maximum around day 4 and persisting until the second week. Vasospasm was significantly associated with a poor outcome (p < 0.05). There was no correlation between the extent of SAH as seen on CT and vasospasm. Evidence of hyperaemia were observed in two patients (8%) and impaired autoregulation in seven patients (29%). Impaired autoregulation was significantly associated with development of hyperaemia (p < 0.05). TCCS studies permit a non-invasive evaluation of cerebral haemodynamics that will help in the management of head injured patients.
机译：对24名严重颅脑损伤（GCS为8或更低）的成年患者进行了连续经颅彩色双工超声检查（TCCS）。从大脑中动脉（MCA）和颅外颈内动脉（EICA）获得流速。使用短暂性充血反应测试进行了自动调节研究，在9例患者中发现了血管痉挛的证据（V-MCA大于100 cm / s，Lindegaard比率大于3）（37％）。其中两个发生了非挫伤相关的梗塞，另外两个发生了挫伤相关的梗塞。这是显着的（p <0.05）。血管痉挛在第2天左右开始出现，在第4天左右达到最大值，并持续到第二周。血管痉挛与不良预后显着相关（p <0.05）。在CT上看到的SAH程度与血管痉挛之间没有相关性。两名患者（8％）出现了充血的证据，而七名患者（29％）的自动调节受损。自身调节受损与充血发展显着相关（p <0.05）。 TCCS研究允许对脑血流动力学进行非侵入性评估，这将有助于头部受伤患者的治疗。

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