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首页> 外文期刊>British journal of neurosurgery >Ventriculostomy-related infections: The performance of different definitions for diagnosing infection
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Ventriculostomy-related infections: The performance of different definitions for diagnosing infection

机译:心室造口术相关感染:诊断感染的不同定义的表现

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Introduction. Comparison of rates of ventriculostomy-related infections (VRIs) across institutions is difficult due to the lack of a standard definition. We sought to review published definitions of VRI and apply them to a test cohort to determine the degree of variability in VRI diagnosis. Materials and methods. We conducted a PubMed search for definitions of VRI using the search strings "ventriculostomy-related infection" and "ventriculostomy-associated infection." We applied these definitions to a test cohort of 18 positive cerebrospinal fluid (CSF) cultures taken from ventriculostomies at two institutions to compare the frequency of infection using each definition. Results. We found 16 unique definitions of VRI. When the definitions were applied to the test cohort, the frequency of infection ranged from 22 to 94% (median 61% with interquartile range (IQR) 56-74%). The concordance between VRI diagnosis and treatment with VRI-directed antibiotics for at least seven days ranged from 56 to 89% (median: 72%, IQR: 71-78%). Conclusions. The myriad of definitions in the literature produce widely different frequencies of infection. In order to compare rates of VRI between institutions for the purposes of qualitative metrics and research, a consistent definition of VRI is needed.
机译:介绍。由于缺乏标准定义,很难比较各个机构的脑室造口相关感染率(VRI)。我们试图审查已公布的VRI定义,并将其应用于测试队列,以确定VRI诊断的变异程度。材料和方法。我们使用搜索字符串“脑室造口术相关感染”和“脑室造口术相关感染”对PubMed进行了VRI定义的搜索。我们将这些定义应用于从两个机构的脑室切开术获得的18种阳性脑脊液(CSF)培养物的测试队列中,以比较每种定义的感染频率。结果。我们发现了VRI的16个独特定义。当将定义应用于测试队列时,感染的频率范围为22%至94%(中位数61%,四分位间距(IQR)56-74%)。 VRI定向抗生素治疗至少7天的VRI诊断与一致性介于56%至89%之间(中位数:72%,IQR:71-78%)。结论文献中的各种定义产生了广泛不同的感染频率。为了比较机构之间的VRI率,以进行定性指标和研究,需要一个一致的VRI定义。

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