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首页> 外文期刊>British journal of neurosurgery >Clinical and methodological confounders in assessing the cerebellar cognitive affective syndrome in adult patients with posterior fossa tumours
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Clinical and methodological confounders in assessing the cerebellar cognitive affective syndrome in adult patients with posterior fossa tumours

机译：评估成年后颅窝肿瘤小脑认知情感综合症的临床和方法学混杂因素

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摘要

The cerebellar cognitive affective syndrome (CCAS) was first described by Schmahmann and Sherman as a constellation of symptoms including dysexecutive syndrome, spatial cognitive deficit, linguistic deficits and behavioural abnormalities in patients with a lesion in the cerebellum with otherwise normal brain. Neurosurgical patients with cerebellar tumours constitute one of the cohorts in which the CCAS has been described. In this paper, we present a critical review of the literature of this syndrome in neurosurgical patients. Thereafter, we present a prospective clinical study of 10 patients who underwent posterior fossa tumour resection and had a detailed post-operative neuropsychological, neuropsychiatric and neuroradiological assessment. Because our findings revealed a large number of perioperative neuroradiological confounding variables, we reviewed the neuroimaging of a further 20 patients to determine their prevalence.
机译：小脑认知情感综合症（CCAS）首先由Schmahmann和Sherman描述为一系列症状，包括执行异常的综合症，空间认知缺陷，语言缺陷和行为异常的小脑病变患者。患有小脑肿瘤的神经外科患者构成了描述CCAS的队列之一。在本文中，我们对神经外科患者中该综合征的文献进行了严格的综述。此后，我们提出了一项对10例行后颅窝肿瘤切除术并进行了详细的术后神经心理学，神经精神病学和神经放射学评估的患者的前瞻性临床研究。因为我们的发现揭示了围手术期大量神经放射学混杂因素，所以我们回顾了另外20例患者的神经影像以确定其患病率。

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