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Role of endoscopy in recalcitrant intraventricular tuberculoma-innovative novel treatment adjunct

机译:内镜在顽固性脑室内结核创新治疗中的作用

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Introduction. lntraventricular tuberculomas are rare entities. To the best of our knowledge, only 14 cases have been reported in English literature. Medical management of cerebral tuberculomas is well accepted. Intraventricular tuberculomas may be recalcitrant for unclear reasons. An effective management protocol for this entity is unclear. To the best of our knowledge, the definitive indication, timing, and possible role of surgery in these lesions have not been discussed in literature. Materials and methods. A 27-year-old nursing professional who was undergoing treatment for miliary tuberculosis at another center presented to us in 2008 with right hemiparesis, deteriorating vision, and progressive decline in consciousness. In addition to antituberculous therapy (ATT), she underwent multiple CSF diversion procedures for the obstructive hydrocephalus secondary to a recalcitrant third ventricular tuberculoma. Finally, she underwent endoscopic decompression of the lesion with a very good clinical response at 1-year follow-up. Discussion. We discuss a patient with recalcitrant intraventricular tuberculoma managed using neuroendoscopy along with the standard antituberculous therapy. We also discuss in detail the technique we utilized for endoscopic management of this lesion. Conclusion. Being a rare entity, a consensus for management of these lesions is not possible, but we have demonstrated that neuroendoscopic management of these rare entities is an option giving the advantage of definitive diagnosis when required, hastening the resolution, and clearing the CSF pathway.
机译:介绍。脑室内结核是罕见的实体。据我们所知,英语文献中仅报道了14例。脑结核的医疗管理已广为接受。由于不清楚的原因,脑室内结核可能会变得顽固。该实体的有效管理协议尚不清楚。据我们所知,在这些病变中确定的适应症,手术时机和可能的作用尚未在文献中讨论。材料和方法。一位27岁的护理专业人员在另一个中心接受了粟粒型肺结核的治疗,于2008年向我们展示了右半身偏瘫,视力下降和意识逐渐下降的情况。除了抗结核治疗(ATT)外,她还因顽固性第三脑室结核继发的阻塞性脑积水接受了多种CSF转移程序。最后,她在1年的随访中接受了内镜下病变的减压治疗,临床反应非常好。讨论。我们讨论了使用神经内镜和标准抗结核疗法治疗的顽固性脑室内结核患者。我们还将详细讨论用于该病灶的内窥镜处理的技术。结论。作为一种罕见的实体,不可能就这些病变的治疗达成共识,但是我们已经证明,对这些罕见实体进行神经内窥镜处理是一种选择,它在需要时具有明确诊断的优势,可加快分辨率并清除CSF途径。

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