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首页> 外文期刊>International Journal of Zoology >Coelomocytes: Biology and Possible Immune Functions in Invertebrates with Special Remarks on Nematodes
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Coelomocytes: Biology and Possible Immune Functions in Invertebrates with Special Remarks on Nematodes

机译：鞘细胞：线虫的特殊标记的无脊椎动物的生物学和可能的免疫功能。

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摘要

All metazoans are exposed to a wide range of microbes and have evolved complex immune defenses used to repel infectious agents. Coelomocytes play a key role in the defense reactions of most invertebrates. They are involved in important immune functions, such as phagocytosis, encapsulation, graft rejection, and inflammation, as well as the synthesis and secretion of several humoral factors especially in annelids and echinoderms. Coelomocytes in nematodes are variable in shapes from round, ovoid, cuboidal, and spindle-shaped to stellate or branched cells that are found usually at fixed positions in the pseudocoelom. Their number usually varies from 2 to 6. The model nematode, C. elegans lacks an adaptive immune system and the Coelomocytes are capableof endocytosis, but their involvement in phagocytosis of bacteria seems unlikely. The aim of this review is to evaluate current knowledge on Coelomocytes of invertebrates with special reference to nematodes. The morphology and structure of these Coelomocytes are discussed along with their origin. Their relative positions and diversity in different nematode groups have also been discussed and illustrated.
机译：所有后生动物都暴露于广泛的微生物中，并且已经进化出用于排斥传染病的复杂免疫防御系统。鞘细胞在大多数无脊椎动物的防御反应中起关键作用。它们参与重要的免疫功能，例如吞噬作用，包囊，移植物排斥和炎症，以及几种体液因子的合成和分泌，尤其是在肘突和棘皮动物中。线虫中的鞘细胞的形状从圆形，卵形，长方体和纺锤形到星状或分支细胞不等，这些细胞通常位于伪腔中的固定位置。它们的数量通常在2到6之间变化。线虫模型线虫缺乏适应性免疫系统，而粒细胞具有内吞能力，但似乎不大可能参与细菌的吞噬作用。这篇综述的目的是评估关于线虫的无脊椎动物的鞘细胞的当前知识。讨论了这些内皮细胞的形态和结构及其起源。还讨论了它们在不同线虫组中的相对位置和多样性。

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