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首页> 外文期刊>International ophthalmology >Prophylactic use of timolol maleate to prevent intraocular pressure elevation after Nd-YAG laser posterior capsulotomy.
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Prophylactic use of timolol maleate to prevent intraocular pressure elevation after Nd-YAG laser posterior capsulotomy.

机译：预防性使用马来酸噻吗洛尔可防止Nd-YAG激光后囊切开术后眼压升高。

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摘要

PURPOSE: To evaluate the effective prophylaxis of topical 0.5% timolol maleate for the intraocular pressure rise following Nd-YAG laser posterior capsulotomy. METHODS: A total of 190 eyes of 184 patients who underwent Nd-YAG laser posterior capsulotomy were randomly assigned to pre-treatment with either topical application of 0.5% timolol maleate (treatment group) or nothing (control group). RESULTS: The mean intraocular pressure (IOP) of the treatment group was 14.8+/-3.0 mmHg before capsulotomy and 15.7+/-3.4 mmHg after capsulotomy (P>0.05), whereas IOP was 15.1+/-3.3 mmHg and 17. 2+/-4.3 mmHg (P<0.05) for the control group. There was no statistically significant difference between the two groups with regard to mean IOP before capsulotomy (P>0.05), but a statistically significant difference was seen between the two groups after capsulotomy (P<0.05). Six of 91 eyes (6.6%, two with aphakia) in the treatment group had an IOP elevation greater than 6 mmHg compared with 14 of 99 eyes (14.1%, eight with aphakia) in the control group (P<0.01). CONCLUSION: Pre-treatment with a topical application of 0.5% timolol maleate is effective in preventing IOP elevation after Nd-YAG laser posterior capsulotomy.
机译：目的：评估局部用0.5％马来酸噻吗洛尔对Nd-YAG激光后囊切开术后眼内压升高的有效预防措施。方法：将接受Nd-YAG激光后囊切开术的184例患者中的190眼随机分配为局部应用0.5％马来酸替莫洛尔（治疗组）或不进行局部治疗（对照组）的预处理。结果：治疗组的平均眼压（IOP）在切囊前为14.8 +/- 3.0 mmHg，在切囊后为15.7 +/- 3.4 mmHg（P> 0.05），而IOP为15.1 +/- 3.3 mmHg和17。2对照组为+/- 4.3 mmHg（P <0.05）。两组患者的平均眼压均无统计学差异（P> 0.05），但两组患者的平均眼压差异无统计学意义（P <0.05）。治疗组的91只眼中有6只眼（6.6％，无晶状体2只）的眼压升高大于6 mmHg，而对照组的99只眼中有14只眼（14.1％，无晶状体8只）（P <0.01）。结论：局部应用0.5％马来酸噻吗洛尔进行预处理可有效预防Nd-YAG激光后囊切开术后眼压升高。

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