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Prophylactic Use of Timolol Maleate to Prevent Intraocular Pressure Elevtion after Nd-YAG Laser Posterior Capsulolomy

机译:预防性使用蒂莫尔马来酸,防止人工压力提升在ND-YAG激光后毛细血管后

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Objective: To evaluate the effective prophylaxis of topical 0.5% timolol maleate for the intraocular pressure rise following Nd-YAG laser posterior capsulotomy. Subjects and Methods: One hundred and ninety eyes of 184 patients undergoing Nd-YAG laser posterior capsulotomy were randomly assigned to pretreatment with either topical 0.5% timolol maleate (therapy group) or nothing (control group). Results: The mean IOP of the therapy group was 14.8?.0 mmHg before capsulotomy and 15.7?.4 mmHg after capsulotomy (P>0.05), whereas 15.1?.3 mmHg and 17.2?.3 mmHg (P<0.05) of the control group. There was no statistically significant difference between the two groups with regard to mean IOP before capsulotomy (P>0.05), but statistically significant difference between two groups after capsulotomy (P<0.05). Six of 91 eyes (6.6%, 2 aphakias included) of the therapy group had an IOP elevation greater than 6 mmHg compared with 14 of 99 eyes (14.1%, 8 aphakias included) of the control group (P<0.01). Conclusion: The pretreatment with topical 0.5% timolol maleate is effective in preventing IOP elevation after Nd-YAG laser posterior capsulotomy.
机译:目的:评价ND-YAG激光后胶囊切开术后的眼压升高的局部0.5%蒂洛尔马来酸的有效预防。受试者和方法:184例接受ND-YAG激光后胶囊术术患者的一百九十只眼时被随机分配给预处理,用局部0.5%蒂莫尔马来酸(治疗组)或没有(对照组)。结果:治疗组的平均IOP为14.8〜.0mmHg,在毛囊术前,15.7毫升(p> 0.05)后15.7mmHg(p> 0.05),而15.1?。3 mmHg和17.2?。3 mmHg(P <0.05)控制组。两组在毛细管切开术前的平均IOP方面没有统计学上显着差异(P> 0.05),但在胶囊术后两组之间的统计学显着差异(P <0.05)。的91眼六(6.6%,2个aphakias包括在内)的治疗组有一个IOP升高大于6毫米汞柱,与对照组(P <0.01)的99 14的眼(14.1%,8个aphakias包括)进行比较。结论:局部0.5%蒂莫尔马来酸的预处理是有效预防ND-YAG激光后胶囊术后IOP升高。

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