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首页> 外文期刊>Investigative ophthalmology & visual science >Time course of changes in ocular higher-order aberrations and contrast sensitivity after overnight orthokeratology.
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Time course of changes in ocular higher-order aberrations and contrast sensitivity after overnight orthokeratology.

机译：过夜角膜塑形术后眼部高阶像差和对比敏感度变化的时程。

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PURPOSE: To investigate prospectively the time course of changes in ocular higher-order aberration and contrast sensitivity after overnight orthokeratology. METHODS: Data from 34 eyes of 17 patients who completed 1-year follow-up examinations were analyzed. The manifest refraction was -2.17 +/- 0.86 D at baseline. Ocular higher-order aberrations for a 4-mm pupil were measured, and the root-mean-square (RMS) of the third-, fourth-, and total higher-order aberrations were determined. Contrast sensitivity was assessed at four spatial frequencies, and the area under the log contrast sensitivity function (AULCSF) was calculated. These examinations were performed before and 1, 2, 3, 6, and 12 months after commencement of the procedure. RESULTS: The treatment significantly increased third-, fourth-, and total higher-order RMS (all P < 0.0001, paired t-test). Log contrast sensitivity significantly decreased at all four spatial frequencies, and AULCSF was also significantly reduced after the treatment (P < 0.0001). To assess the time course of changes in these parameters, posttreatment data were analyzed by using repeated-measures analysis of variance. There were no significant fluctuations in manifest refraction; uncorrected visual acuity; third-, fourth-, and total higher-order RMS; and AULCSF (all P > 0.05). In addition, there was no significant variance in log contrast sensitivity at each spatial frequency during the 1-year follow-up period (all P > 0.05). CONCLUSIONS: The initial reduction in optical quality of the eye and quality of vision after the procedure is stable during the treatment period of at least 1 year, and the reduction does not worsen further after 1 month. Orthokeratology candidates should be fully informed of these changes.
机译：目的：前瞻性研究过夜角膜塑形术后眼高阶像差和对比敏感度变化的时间过程。方法：分析了完成1年随访检查的17例患者的34只眼的数据。基线时的明显折射为-2.17 +/- 0.86D。测量了4毫米瞳孔的眼部高阶像差，并确定了第三，第四和总高阶像差的均方根（RMS）。在四个空间频率处评估对比敏感度，并计算对数对比敏感度函数（AULCSF）下的面积。这些检查是在手术开始之前，1、2、3、6和12个月之后进行的。结果：治疗显着增加了第三，第四和总的高阶RMS（所有P <0.0001，配对t检验）。在所有四个空间频率下，对数对比灵敏度均显着降低，并且治疗后AULCSF也显着降低（P <0.0001）。为了评估这些参数变化的时间过程，使用重复测量方差分析对后处理数据进行了分析。明显屈光没有明显的波动。未矫正的视力;三阶，四阶和总高阶RMS;和AULCSF（所有P> 0.05）。此外，在1年的随访期间，每个空间频率的对数对比灵敏度均无显着差异（所有P> 0.05）。结论：在至少一年的治疗期间，手术后眼睛的光学质量和视力质量的初始下降是稳定的，并且在1个月后这种下降不会进一步恶化。角膜塑形术候选人应充分了解这些变化。

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