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首页> 外文期刊>Investigative ophthalmology & visual science >Evaluation of macular function using focal macular electroretinography in eyes with macular edema associated with branch retinal vein occlusion
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Evaluation of macular function using focal macular electroretinography in eyes with macular edema associated with branch retinal vein occlusion

机译：黄斑水肿与分支视网膜静脉阻塞相关的黄斑水肿，使用聚焦黄斑视网膜电图评价黄斑功能

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Purpose. To study the usefulness of focal macular electroretinography (fmERG) for evaluation of macular function in eyes with macular edema (ME) associated with branch retinal vein occlusion (BRVO). Methods. The authors prospectively performed fmERG on 34 patients with untreated unilateral BRVO at the initial visit and 12 months later. Amplitudes and latencies of the a-wave, b-wave, and photopic negative response (PhNR) were compared with visual acuity, with retinal sensitivity measured by microperimetry, and with measurements obtained by optical coherence tomography. Results. In eyes with ME from BRVO, amplitudes of the a-wave, b-wave, and PhNR were reduced significantly and latencies were prolonged significantly compared with those of healthy fellow eyes (P < 0.05). Relative amplitudes and latencies were not correlated with visual acuity but, rather, tended to be correlated with retinal sensitivity within the macular area. Among all parameters studied by fmERG, relative amplitude of the PhNR was most strongly correlated with central foveal thickness (r = -0.465; P = 0.007). In addition, the height of the serous retinal detachment showed a correlation with the relative amplitude of the PhNR (r = -0.376; P = 0.034). At 12 months, the amplitude of the b-wave and the PhNR improved significantly, in parallel with resolution of the ME (P = 0.015; P = 0.033). Conclusions. In eyes with ME from BRVO, amplitudes and latencies seen by fmERG were correlated with other biological parameters. Based on findings of the present study, fmERG appears to be useful as a functional examination within the macular area affected by BRVO.
机译：目的。目的研究局部黄斑视网膜电图（fmERG）在评估视网膜黄斑水肿（ME）伴视网膜分支静脉阻塞（BRVO）的眼中黄斑功能的有效性。方法。作者在首次就诊时和12个月后对34例未经治疗的单侧BRVO患者进行了fmERG的前瞻性研究。将a波，b波和明眼负反应（PhNR）的幅度和潜伏期与视敏度，通过微视野测量法测量的视网膜灵敏度以及通过光学相干断层扫描获得的测量值进行比较。结果。与健康的其他人相比，患有BRVO的ME眼的a波，b波和PhNR幅度均显着降低，并且潜伏期显着延长（P <0.05）。相对振幅和潜伏期与视敏度不相关，而是倾向于与黄斑区域内的视网膜敏感性相关。在通过fmERG研究的所有参数中，PhNR的相对幅度与中央凹的厚度最密切相关（r = -0.465; P = 0.007）。此外，浆液性视网膜脱离的高度与PhNR的相对幅度相关（r = -0.376; P = 0.034）。在12个月时，b波和PhNR的幅度显着改善，与ME的分辨率平行（P = 0.015; P = 0.033）。结论在患有BRVO的ME眼中，fmERG观察到的振幅和潜伏期与其他生物学参数相关。基于本研究的发现，fmERG似乎可作为受BRVO影响的黄斑区域的功能检查。

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