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首页> 外文期刊>Investigative radiology >Blood Velocity Calculated From Volumetric Dynamic Computed Tomography Angiography
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Blood Velocity Calculated From Volumetric Dynamic Computed Tomography Angiography

机译：从体积动态计算机断层扫描血管造影术计算的血流速度

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Objective: Though' functional intravascular parameters such as blood velocity and direction of blood flow are available via imaging modalities such as Doppler ultrasound and phase contrast magnetic resonance imaging, such quantitative information is not yet supported by computed tomography (CT). In this study, we examined a method to calculate intra-arterial blood velocity from contrast-enhanced dynamic CT angiography (4D CTA) using the unique advantages of a volumetric 320 detector row scanner. Materials and Methods: Contrast boluses were injected into a flow phantom under volumetric 4D CTA examination. Two pipe diameters were tested, each diameter with 4 various flow velocities, creating 8 independent flow conditions. The internal carotid arteries of 5 patients (10 arteries in total) were subjected to a similar dynamic CTA examination and reconstructed with a 1-second temporal resolution through the arterial phase. Intraluminal velocities were calculated using distance between 2 regions of interest placed proximally and distally over the vessel, divided by delay in time to peak of contrast arrival in each region of interest. Results were compared with flow velocities attained by quantitative magnetic resonance angiography in vivo. Results: Phantom experiments demonstrate reasonable agreement between calculated and measured intraluminal velocity (P = 0.05). Similarly, in vivo blood velocity calculations in all internal carotid arteries show agreement with results attained by quantitative magnetic resonance angiography. Conclusions: Intraluminal blood velocity may be estimated from first-pass contrast bolus profiles acquired via volumetric 4D CTA examinations.
机译：目的：尽管可以通过诸如多普勒超声和相衬磁共振成像等成像方式获得诸如血流速度和血流方向等功能性血管内参数，但计算机断层扫描（CT）尚不支持这种定量信息。在这项研究中，我们研究了一种使用容积式320行探测器行扫描仪的独特优势，通过增强造影剂动态CT血管造影术（4D CTA）计算动脉血流速度的方法。材料和方法：在体积4D CTA检查下将造影剂注入流模型中。测试了两个管道直径，每个直径具有4种不同的流速，创建了8个独立的流动条件。对5名患者的颈内动脉（总共10条动脉）进行了相似的动态CTA检查，并在整个动脉期以1秒的时间分辨率重建。使用放置在血管近端和远端的两个感兴趣区域之间的距离计算腔内速度，除以到达每个感兴趣区域的造影剂到达峰值的时间延迟。将结果与体内定量磁共振血管造影获得的流速进行比较。结果：幻影实验表明，腔内速度的计算值与测量值之间具有合理的一致性（P = 0.05）。同样，所有颈内动脉的体内血流速度计算均与定量磁共振血管造影获得的结果一致。结论：可以通过通过容积4D CTA检查获得的首过造影剂推注曲线估算腔内血流速度。

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