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首页> 外文期刊>International journal of surgical pathology >Oncocytic Carcinoma of the Submandibular Gland: A Case Report
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Oncocytic Carcinoma of the Submandibular Gland: A Case Report

机译：下颌下腺癌的一例报告

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Oncocytic carcinoma (OC) of the submandibular gland is extremely rare. A 76-year-old man complained of a painless tumor of the right neck. Ultrasonography demonstrated swelling in the lymph nodes of the neck, and fine-needle aspiration cytology of a node showed metastatic carcinoma with oncocytic features. Radical surgery revealed infiltrating carcinoma of the right submandibular gland with lymph node metastases (19/23). Tumor cells showed less atypia and had abundant eosinophilic cytoplasm, which stained deep blue with phosphotungstic acid-hematoxylin stain. The cells were immunohistochemically positive for cytokeratin 7 but negative for p63 and SOX10. We diagnosed the tumor as OC. Chemoradiotherapy was performed after surgery. The patient showed no sign of recurrence until 42 months after the operation, when lymph node swelling was detected in the mediastinum by computed tomography scanning. With no further treatment, the patient is alive with lymph node swellings in the mediastinum and pulmonary hilum 80 months after surgery.
机译：下颌下腺癌（OC）非常罕见。一名76岁的男子抱怨右颈部无痛。超声检查显示颈部淋巴结肿大，淋巴结细针穿刺细胞学检查显示转移性癌具有吞噬功能。根治性手术显示右下颌浸润癌伴淋巴结转移（19/23）。肿瘤细胞显示出较少的异型性，并具有丰富的嗜酸性细胞质，其被磷钨酸-苏木精染色为深蓝色。细胞对细胞角蛋白7免疫组织化学阳性，对p63和SOX10阴性。我们将肿瘤诊断为OC。手术后进行放化疗。直到手术后42个月，该患者才显示出复发迹象，当时通过计算机断层扫描发现纵隔中有淋巴结肿大。无需进一步治疗，患者在手术80个月后仍存在纵隔和肺门淋巴结肿大。

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