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Genetic variation and association of insulin-like growth factor binding protein-3 with performance in Swine.

机译:猪中胰岛素样生长因子结合蛋白3的遗传变异及其与生产性能的关系。

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摘要

Genetic variation of insulin-like growth factor binding protein-3 was analyzed in 17 pig breeds (14 native Chinese and 3 European). Using PCR-single strand conformation polymorphism, we found a polymorphism in intron 2, and this SNP was the combined mutation of G897T-G903A-C911T. The Chinese breeds carried a higher TAT/TAT genotype frequency (over 50%), except for Bamei (22%), Yujiang Black (0.0%), and Erhualian (10.0%); the European breeds had a higher GGC/GGC genotype frequency (Large White 1.67%, Landrace 13.89%, Duroc 0.0%). The allelic frequency of TAT in Chinese breeds was over 50%, except for Yujiang Black (12.5%); the allelic frequency of GGC was over 50% in all European breeds. The effect of genotype on 43 performance traits was investigated in one population (Lantang x Landrace). Pigs with the TAT/TAT genotype had higher B-point and C-point back-fat thickness than pigs with the GGC/GGC genotype. The TAT/TAT pigs also scored higher in meat color than the GGC/GGC pigs. These results implied that IGFBP-3 may affect meat quality and carcass traits.
机译:分析了17个猪品种(14个中国本地人和3个欧洲人)中胰岛素样生长因子结合蛋白3的遗传变异。使用PCR-单链构象多态性,我们在内含子2中发现了一个多态性,该SNP是G897T-G903A-C911T的组合突变。中国品种的TAT / TAT基因型频率较高(超过50%),除八美(22%),玉江黑(0.0%)和二花脸(10.0%)外。欧洲品种的GGC / GGC基因型频率更高(大白1.67%,长白13.89%,杜洛克0.0%)。除玉江黑(12.5%)外,中国品种的TAT等位基因频率超过50%。在所有欧洲品种中,GGC的等位基因频率均超过50%。在一个人群中(Lantang x Landrace),研究了基因型对43个性能特征的影响。具有TAT / TAT基因型的猪比具有GGC / GGC基因型的猪具有更高的B点和C点背脂厚度。 TAT / TAT猪的肉色得分也比GGC / GGC猪高。这些结果表明,IGFBP-3可能会影响肉质和car体性状。

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