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首页> 外文期刊>Electrophoresis: The Official Journal of the International Electrophoresis Society >Dielectrophoresis of spermatozoa in viscoelastic medium
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Dielectrophoresis of spermatozoa in viscoelastic medium

机译：粘弹性介质中精子的介电泳

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Knowledge of spermatozoa motility is important in selecting suitable spermatozoa for assisted reproduction procedures. By considering the internal sliding force within an active filament, its shape in a viscoelastic Oldroyd-B fluid subjected to nonuniform electric field is presented. The resulting velocity is a function of the beating pattern and DEP force, which is dependent on the spermatozoon's morphology as well as the gradient of the mean square electric field. Finally, the velocities of the X- and Y-spermatozoa are compared under various conditions of nonuniform electric field and viscoelasticity of the medium. The presence of DEP force alters their velocities to different extents, giving an 84% level of confidence for selecting spermatozoon that contains the chromosome leading to a female. Therefore, a nonuniform electric field can be used not only to sort and select spermatozoa of desired morphology, but also for gender selection. Moreover, we found that sorting in a viscoelastic fluid medium is more effective as the effect of DEP on the spermatozoa velocity is enhanced by an order of magnitude.
机译：精子运动性的知识对于选择合适的精子用于辅助生殖过程很重要。通过考虑活性细丝内的内部滑动力，提出了在不均匀电场作用下的粘弹性Oldroyd-B流体中其形状。产生的速度是拍打模式和DEP力的函数，它取决于精子的形态以及均方电场的梯度。最后，比较了在非均匀电场和介质粘弹性的各种条件下X和Y精子的速度。 DEP力的存在在不同程度上改变了它们的速度，为选择包含导致雌性染色体的精子提供了84％的置信度。因此，不均匀的电场不仅可以用于分类和选择所需形态的精子，而且可以用于性别选择。此外，我们发现在粘弹性流体介质中进行分选更为有效，因为DEP对精子速度的影响提高了一个数量级。

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