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Overview of endocrine systems in primary hypertension.

机译:原发性高血压的内分泌系统概述。

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摘要

Multiple hormonal factors play a major role in the functional and structural abnormalities of hypertension (HT). At present, the kidneys and, in particular, renal Na(+) retention are thought to constitute a primary and sustaining mechanism in the development of HT. However, the precise renal and hormonal mechanisms leading to increased Na(+) reabsorption and HT remain unknown. Because the vast majority of HT is primary, this article focuses on the major endocrine systems, the RAS, aldosterone, and the SNS, that play a prominent role in the pathogenesis of HT.
机译:多种激素因素在高血压(HT)的功能和结构异常中起主要作用。目前,肾脏,尤其是肾脏的Na(+)保留被认为是HT形成的主要和维持机制。但是,导致增加的Na(+)重吸收和HT的确切的肾脏和激素机制仍然未知。由于绝大多数HT是原发性的,因此本文重点介绍在HT发病机理中起重要作用的主要内分泌系统RAS,醛固酮和SNS。

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