The clinical relevance of chromogranin a as a biomarker for gastroenteropancreatic neuroendocrine tumors.

Lawrence B; Gustafsson BI; Kidd M; Pavel M; Svejda B; Modlin IM

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The clinical relevance of chromogranin a as a biomarker for gastroenteropancreatic neuroendocrine tumors.

机译：嗜铬粒蛋白a作为胃肠道胰腺神经内分泌肿瘤的生物标志物的临床意义。

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Chromogranin A, although it exhibits limitations, is currently the most useful general tumor biomarker available for use in the diagnosis and management of gastroenteropancreatic neuroendocrine tumors (NETs). The value of the chromogranin A lies in its universal cosecretion by the majority of neuroendocrine cells that persists after malignant transformation. Clinicians aware of the physiologic role of chromogranin A and its secretion in a variety of non-NET-related pathologic conditions can use this protein as a moderately effective tumor biomarker in the management of GEP-NETs.

机译：嗜铬粒蛋白A尽管表现出局限性，但目前是可用于诊断和管理胃肠道胰腺神经内分泌肿瘤（NETs）的最有用的一般肿瘤生物标志物。嗜铬粒蛋白A的价值在于其在大多数神经内分泌细胞的普遍共分泌中，这些神经内分泌细胞在恶性转化后仍然存在。临床医生了解嗜铬粒蛋白A的生理作用及其在各种非NET相关病理状况中的分泌，可以将该蛋白用作GEP-NETs治疗中度有效的肿瘤生物标志物。

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《Endocrinology and Metabolism Clinics of North America》 |2011年第1期|共25页
作者
Lawrence B; Gustafsson BI; Kidd M; Pavel M; Svejda B; Modlin IM;
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正文语种 eng
中图分类内分泌腺疾病及代谢病;
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1. The clinical relevance of chromogranin a as a biomarker for gastroenteropancreatic neuroendocrine tumors. [J] . Lawrence B, Gustafsson BI, Kidd M, Endocrinology and Metabolism Clinics of North America . 2011,第1期

机译：嗜铬粒蛋白a作为胃肠道胰腺神经内分泌肿瘤的生物标志物的临床意义。
2. Biomarkers and molecular imaging in gastroenteropancreatic neuroendocrine tumors. [J] . Lindholm DP, Oberg K Hormone and Metabolic Research . 2011,第12期

机译：胃肠胰腺神经内分泌肿瘤的生物标志物和分子成像。
3. Chromogranin A: A sensitive biomarker for the detection and post-treatment monitoring of gastroenteropancreatic neuroendocrine tumors [J] . SinghS., LawC. Expert review of gastroenterology & hepatology . 2012,第3期

机译：嗜铬粒蛋白A：一种敏感的生物标志物，用于检测和治疗胃肠道胰腺神经内分泌肿瘤
4. The clinical relevance of biomarkers of exercise-induced myocardial stress in athletes [C] . Dickhuth H.H., Konig D. European Sports Medicine Congress . 2009

机译：运动诱导的运动员心肌压力生物标志物的临床相关性
5. Improving Survival Prognostication of Gastroenteropancreatic Neuroendocrine Tumors [D] . Martin, Jacob A. 2017

机译：改善胃肠道胰腺神经内分泌肿瘤的生存预后
6. Circulating Chromogranin A as A Marker for Monitoring Clinical Response in Advanced Gastroenteropancreatic Neuroendocrine Tumors [O] . Tiantian Tian, Jing Gao, Na Li, -1

机译：循环嗜铬粒蛋白A标记监测晚期胃肠道胰腺神经内分泌肿瘤的临床反应
7. Circulating Chromogranin A as A Marker for Monitoring Clinical Response in Advanced Gastroenteropancreatic Neuroendocrine Tumors. [O] . Tiantian Tian, Jing Gao, Na Li, 2016

机译：循环嗜铬粒蛋白a作为监测晚期胃肠胰腺神经内分泌肿瘤临床反应的标志物。

The clinical relevance of chromogranin a as a biomarker for gastroenteropancreatic neuroendocrine tumors.

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