Isotretinoin Oxidation and Electroanalysis in a Pharmaceutical Drug Using a Boron-doped Diamond Electrode

Machini W. B. S.; Enache T. A.; Jorge S. M. A.; Oliveira-Brett A. M.

首页> 外文期刊>Electroanalysis >Isotretinoin Oxidation and Electroanalysis in a Pharmaceutical Drug Using a Boron-doped Diamond Electrode

【24h】

Isotretinoin Oxidation and Electroanalysis in a Pharmaceutical Drug Using a Boron-doped Diamond Electrode

机译：掺硼金刚石电极在药物中异维A酸的氧化和电分析

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

Isotretinoin redox behaviour, by voltammetry, at the cathodic pre-treated boron doped diamond electrode by cyclic, differential pulse and square wave voltammetry, and by spectrophotometry in a wide pH range, was investigated. The isotretinoin oxidation was an irreversible, diffusion-controlled process, occurred in a three-step cascade mechanism, and the isotretinoin diffusion coefficient D13-cis-RA=7.35x10(-6)cm(2)s(-1), was calculated. The UV-Vis isotretinoin maximum absorption was pH-dependent. The detection limits LOD=0.53M, by differential pulse voltammetry, and LOD=0.38M, by UV-Vis spectroscopy, were obtained. The isotretinoin in the pharmaceutical drug Roacutan((R)), using differential pulse voltammetry, was determined.

机译：通过循环伏安法，差示脉冲法和方波伏安法在宽pH范围内用分光光度法研究了阴极预处理的硼掺杂金刚石电极上的异维A酸氧化还原行为。异维A酸的氧化是不可逆的扩散控制过程，发生在三步级联机制中，计算出异维A酸的扩散系数D13-cis-RA = 7.35x10（-6）cm（2）s（-1）。。 UV-Vis异维A酸的最大吸收是pH依赖性的。通过微分脉冲伏安法获得了检测限LOD = 0.53M，并且通过UV-Vis光谱法获得了LOD = 0.38M。使用差分脉冲伏安法测定了药物Roacutan（R）中的异维A酸。

著录项

来源
《Electroanalysis》 |2016年第11期|共7页
作者
Machini W. B. S.; Enache T. A.; Jorge S. M. A.; Oliveira-Brett A. M.;
展开▼
作者单位

展开▼
收录信息
原文格式 PDF
正文语种 eng
中图分类电化学、电解、磁化学;
关键词
Isotretinoin; 13-cis-retinoic acid; Electrochemical oxidation; Boron-Doped Diamond;

机译：异维A酸;13-顺维甲酸;电化学氧化;掺硼金刚石;

相似文献

外文文献
中文文献
专利

1. 掺硼金刚石电极结合二氧化钛光催化阳极氧化降解苯酚 [J] . 戎非, 顾林娟, 邱烨静, 东南大学学报（英文版） . 2010,第003期
2. Isotretinoin Oxidation and Electroanalysis in a Pharmaceutical Drug Using a Boron-doped Diamond Electrode [J] . Machini W. B. S., Enache T. A., Jorge S. M. A., Electroanalysis . 2016,第11期

机译：掺硼金刚石电极在药物中异维A酸的氧化和电分析
3. Voltammetric Investigation of Antiviral Drug Valacyclovir at a Boron-Doped Diamond Electrode in Different Electrolyte Media: Its Determination Enhanced by Anionic Surfactant in Pharmaceuticals and Biological Fluids [J] . Pinar Pinar Talay, Senturk Zuhre Current pharmaceutical analysis. . 2017,第2期

机译：不同电解质介质中硼掺杂金刚石电极抗病毒药物丙酰吡咯的伏安调查：其药物和生物液中阴离子表面活性剂增强的测定
4. Occurrence of pharmaceuticals, illicit drugs, and resistant types of bacteria in hospital effluent and their effective degradation by boron-doped diamond electrodes [J] . Mackulak Tomas, Vojs Marian, Grabic Roman, Monatshefte fur Chemie . 2016,第1期

机译：医院废水中药物，非法药物和细菌的耐药性种类及其掺硼金刚石电极的有效降解
5. ELECTROANALYSIS OF DOPAMINE IN ASCORBIC ACID ON BORON-DOPED DIAMOND ELECTRODE [C] . . 2005

机译：掺硼金刚石电极上酸性多巴胺的电分析
6. Electrochemical oxidation of phenol in simulated petrochemical wastewaters using boron-doped diamond electrodes: Investigation of effect of ammonia, carbon nitride and sulfur presence. [D] . Dalhat, Mu'azu Nuhu. 2010

机译：使用掺硼金刚石电极在模拟石化废水中苯酚的电化学氧化：研究氨，氮化碳和硫的存在的影响。
7. High-Temperature Oxidation of Heavy Boron-Doped Diamond Electrodes: Microstructural and Electrochemical Performance Modification [O] . Jacek Ryl, Mateusz Cieslik, Artur Zielinski, 2020

机译：重硼掺杂金刚石电极的高温氧化：微观结构和电化学性能的修改。
8. Voltammetric quantification of an anesthetic drug propofol (2,6-diisopropylphenol) on boron-doped diamond electrode in the pharmaceutical formulations [O] . Ertuğrul Keskin, Shabnam Allahverdiyeva, Hande Özok, 2021

机译：在药物制剂中硼掺杂金刚石电极上的麻醉药物（2,6-二异丙基苯酚）的伏安定量

Isotretinoin Oxidation and Electroanalysis in a Pharmaceutical Drug Using a Boron-doped Diamond Electrode

摘要

著录项

相似文献

相关主题

期刊订阅