...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Electroanalysis >Electrocatalytic determination of 6-tioguanine at a p-aminophenol modified carbon paste electrode
【24h】

Electrocatalytic determination of 6-tioguanine at a p-aminophenol modified carbon paste electrode

机译：对氨基苯酚修饰的碳糊电极电催化测定6-硫代鸟嘌呤

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

A p-aminophenol modified carbon paste electrode (p-APMCPE) was constructed for determination of an anticancer drug 6-thioguanine (6-TG). The cyclic voltammogram showed that the electrocatalytic oxidation of 6-TG at the surface of p-APMCPE occurs at a potential about 840 mV less positive than at an unmodified electrode. Square-wave voltammetry results presented that the electrocatalytic oxidation peak Currents of 6-TG in pH 9.0 had two linear dynamic ranges in the range of 0.2 to 8.0 and 8.0 to 350.0 mu M 6-TG with a detection limit of 0.08 mu M. The kinetic parameters such as electron transfer coefficient (alpha) and rate constant were determined for the chemical reaction between 6-TG and p-aminophenol. Finally, this method was evaluated for the determination of 6-TG in 6-thioguanine tablets and urine samples.
机译：构建了对氨基苯酚修饰的碳糊电极（p-APMCPE），用于测定抗癌药物6-硫鸟嘌呤（6-TG）。循环伏安图显示p-APMCPE表面6-TG的电催化氧化比未修饰电极的正电性低约840 mV。方波伏安法结果表明，6-TG在pH 9.0时的电催化氧化峰电流在0.2-8.0和8.0-350.0μM6-TG范围内具有两个线性动态范围，检出限为0.08μM。确定了6-TG与对氨基苯酚之间的化学反应的动力学参数，如电子传递系数α和速率常数。最后，评估了该方法对6-硫鸟嘌呤片剂和尿液样品中6-TG的测定。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号