...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Electroanalysis >New Protocol for Determination of Rifampicine by Adsorptive Stripping Voltammetry
【24h】

New Protocol for Determination of Rifampicine by Adsorptive Stripping Voltammetry

机译：吸附溶出伏安法测定利福平的新方案

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

For determinations of organic compounds by adsorptive stripping voltammetry till now the same material of the electrode has been used for the accumulation and stripping steps. This paper describes a new protocol for extending the range of organic compounds, which can be determined by adsorptive stripping voltammetry. In the proposed procedure the accumulation step was performed on the electrode modified by a lead film, which assures adsorption of the studied species on the modified electrode and then the stripping step of the accumulated substance was performed on the support of the lead film electrode. As an example rifampicine was accumulated by adsorption at the lead film electrode while in the stripping step lead film and then the accumulated rifampicine were oxidized at a glassy carbon electrode. Using an acetate buffer as a supporting electrolyte a calibration graph for rifampicine in the range from 2.5 x 10(-10) to 1 x 10(-8) mol L-1 was obtained. The detection limit for rifampicine following 60 s accumulation time was equal to 9 x 10(-11) mol L-1. The obtained detection limit was comparable or lower than reported previously for other stripping voltammetric procedures. The proposed procedure was applied to rifampicine determination in pharmaceutical preparation.
机译：迄今为止，为了通过吸附溶出伏安法测定有机化合物，到目前为止，电极的相同材料已用于累积和溶出步骤。本文介绍了一种扩展有机化合物范围的新方案，该方案可以通过吸附溶出伏安法测定。在所提出的程序中，在由铅膜修饰的电极上进行累积步骤，以确保所研究的物质吸附在修饰电极上，然后在铅膜电极的支撑体上进行累积物质的剥离步骤。作为示例，在剥离步骤中，在引线膜电极上通过吸附将利福平累积起来，然后在玻璃碳电极上将积累的利福平氧化。使用乙酸盐缓冲液作为支持电解质，可以得到在2.5 x 10（-10）到1 x 10（-8）mol L-1范围内的利福平校准图。累积60 s后，利福平的检出限等于9 x 10（-11）mol L-1。所获得的检出限与其他汽提伏安法之前报道的相当或更低。拟议的程序用于药物制剂中利福平的测定。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号