Fabrication of an Electrochemical Sensor Based on Multiwalled Carbon Nanotubes for Almotriptan

Prashanth S. Narayan; Nagappa L. Teradal; Shankara S. Kalanur; J. Seetharamappa

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Fabrication of an Electrochemical Sensor Based on Multiwalled Carbon Nanotubes for Almotriptan

机译：基于多壁碳纳米管的阿莫曲普坦电化学传感器的制备

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In the present work, the electrochemical behavior of an antimigraine drug, almotriptan malate (ALM), on a multiwalled carbon nanotube (MWCNT) film modified glassy carbon electrode under cyclic voltammetry was described for the first time. A significant enhancement in the oxidation peak current of ALM was noticed at MWCNT-GCE. This property was exploited to develop a simple, sensitive and time-saving differential pulse voltammetric method for the determination of ALM in bulk and pharmaceutical samples. A linear relationship was observed between concentration and peak current with a correlation coefficient of 0.9915 in the range of 0.25-37.5 μM ALM.

机译：在目前的工作中，首次描述了抗偏头痛药物苹果酸阿莫曲坦（ALM）在多壁碳纳米管（MWCNT）膜修饰的玻碳电极上的循环伏安法的电化学行为。在MWCNT-GCE处发现ALM的氧化峰值电流显着增强。利用该特性开发了一种简单，灵敏且省时的差分脉冲伏安法，用于测定散装和药物样品中的ALM。浓度与峰值电流之间存在线性关系，相关系数为0.9915，在ALM的范围为0.25-37.5μM。

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《Electroanalysis》 |2013年第12期|共7页
作者
Prashanth S. Narayan; Nagappa L. Teradal; Shankara S. Kalanur; J. Seetharamappa;
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正文语种 eng
中图分类电化学、电解、磁化学;
关键词
Almotriptan; Electrochemical sensors; Modified electrodes; Multiwalled carbon nanotubes;

机译：阿莫曲坦;电化学传感器;修饰电极;多壁碳纳米管;

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1. Fabrication of an Electrochemical Sensor Based on Multiwalled Carbon Nanotubes for Almotriptan [J] . Prashanth S. Narayan, Nagappa L. Teradal, Shankara S. Kalanur, Electroanalysis . 2013,第12期

机译：基于多壁碳纳米管的阿莫曲普坦电化学传感器的制备
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Fabrication of an Electrochemical Sensor Based on Multiwalled Carbon Nanotubes for Almotriptan

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