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首页> 外文期刊>Environmental health perspectives. >Indoor environmental exposures for children with asthma enrolled in the HEAL study, post-Katrina New Orleans
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Indoor environmental exposures for children with asthma enrolled in the HEAL study, post-Katrina New Orleans

机译：卡特里娜飓风后新奥尔良的HEAL研究纳入了哮喘儿童的室内环境暴露

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Background: Rain and flooding from Hurricane Katrina resulted in widespread growth of mold and bacteria and production of allergens in New Orleans, Louisiana, which may have led to increased exposures and morbidity in children with asthma. Objectives: The goal of the Head-off Environmental Asthma in Louisiana (HEAL) study was to characterize post-Katrina exposures to mold and allergens in children with asthma. Methods: The homes of 182 children with asthma in New Orleans and surrounding parishes were evaluated by visual inspection, temperature and moisture measurements, and air and dust sampling. Air was collected using vacuum-pump spore traps and analyzed for > 30 mold taxa using bright field microscopy. Dust was collected from the children's beds and bedroom floors and analyzed for mouse (Mus m 1), dust mite (Der p 1), cockroach (Bla g 1), and mold (Alternaria mix) allergens using ELISA. R esults: More than half (62%) of the children were living in homes that had been damaged by rain, flooding, or both. Geometric mean indoor and outdoor airborne mold levels were 501 and 3,958 spores/m3, respectively. Alternaria antigen was detected in dust from 98% of homes, with 58% having concentrations > 10 μg/g. Mus m 1, Der p 1, and Bla g 1 were detected in 60%, 35%, and 20% of homes, respectively, at low mean concentrations. C onclusions: Except for Alternaria antigen in dust, concentrations of airborne mold (ratio of indoor to outdoor mold) and dust allergens in the homes of HEAL children were lower than measurements found in other studies, possibly because of extensive post-Katrina mold remediation and renovations, or because children moved into cleaner homes upon returning to New Orleans.
机译：背景：卡特里娜飓风带来的降雨和洪水导致路易斯安那州新奥尔良的霉菌和细菌大量繁殖，并产生了过敏原，这可能导致哮喘儿童的暴露和发病率增加。目的：路易斯安那州头疼性环境哮喘（HEAL）研究的目的是确定卡特里娜飓风后儿童哮喘和过敏原的暴露状况。方法：通过目视检查，温度和湿度测量以及空气和灰尘采样，对新奥尔良及周围教区的182名哮喘儿童的住所进行了评估。使用真空泵孢子阱收集空气，并使用明场显微镜分析> 30个霉菌类群。从儿童床和卧室地板收集灰尘，并使用ELISA分析小鼠（Mus m 1），螨虫（Der p 1），蟑螂（Bla g 1）和霉菌（Alternaria mix）过敏原。结果：超过一半（62％）的儿童住在因雨水，洪水或两者而损坏的房屋中。室内和室外机载霉菌的几何平均数分别为501和3,958孢子/ m3。在98％的家庭的灰尘中检测到了链霉菌抗原，其中58％的浓度> 10μg/ g。在低平均浓度下，分别在60％，35％和20％的房屋中检测到Mus m 1，Der p 1和Bla g 1。结论：除尘土中的链霉菌抗原外，HEAL儿童家庭中空气传播的霉菌（室内霉菌与室外霉菌的比率）和粉尘过敏原的浓度均低于其他研究中的测量值，这可能是由于卡特里娜飓风后的大量霉菌修复和装修，或因为孩子们返回新奥尔良后搬进了更干净的家。

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