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Surgical resection of gastrointestinal stromal tumor of esophagus following preoperative imatinib treatment: A case report

机译:伊马替尼治疗前食管胃肠道间质瘤的手术切除:一例

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摘要

We report a case of esophagectomy after a primary esophageal gastrointestinal stromal tumor (GIST) was preoperatively treated with imatinib mesylate. A 71-year-old woman was diagnosed with an esophageal submucosal tumor by upper gastrointestinal endoscopy at her health checkup. The tumor was located at the lower thoracic esophagus immediately above the esophagogastric junction and measured 4.5 cm in size. It was diagnosed as GIST of the esophagus for reasons of its high susceptibility to imatinib mesylate. Preoperative treatment with imatinib was performed in an attempt to preserve the esophagus. Although the tumor size was decreased by 36% after the 6-month treatment, transhiatal esophagectomy was required for complete resection, and esophageal preservation could not be accomplished.
机译:我们报告一例原发性食管胃肠道间质瘤(GIST)在术前用甲磺酸伊马替尼治疗后的食管切除术。一名71岁的女性在接受健康检查时被上消化道内窥镜检查诊断为食管粘膜下肿瘤。肿瘤位于食管胃交界处正上方的下胸部食道,大小为4.5厘米。由于其对甲磺酸伊马替尼的高度敏感性,被诊断为食道GIST。为了保护食道,进行了伊马替尼的术前治疗。尽管在6个月的治疗后肿瘤大小减少了36%,但仍需要经全孔食管切除术才能完全切除,并且无法实现食管保存。

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