• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Esophagus >Oral, pharyngeal, and esophageal transit of an acidic bolus in healthy subjects
【24h】

Oral, pharyngeal, and esophageal transit of an acidic bolus in healthy subjects

机译：健康受试者的酸性推注的口腔，咽部和食道转运

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background The swallowing function is influenced by chemical and sensory stimuli. The aim of this investigation was to evaluate the effect of an acidic sour bolus on its oral, pharyngeal, and esophageal transit in healthy volunteers. Method Scintigraphic evaluation of the transit was performed in 43 healthy subjects aged 23-71 years. Each subject swallowed, in a random sequence, 5 mL of two liquid boluses: acidic (50 mL of water with 3 g of concentrated lemon juice, pH 3.0) and neutral (water, pH 6.8), both labeled with 37 MBq of technetium-99m phytate. A series of images of each swallow were acquired at 20 franies/ss for 20 s with the subjects sitting in front of the collimator of the gamma camera.Results There was no difference between neutral and acidic boluses in terms of their transit and clearance durations and in the amount of residues when passing through the mouth and pharynx. In the proximal esophagus, the transit and clearance were longer with the neutral bolus (clearance 1.40 ± 0.11 s) than with the acidic bolus (1.17 ± 0.07 s, p = 0.04). In the distal esophagus, the transit and clearance were longer with the acidic bolus (clearance 10.66 ± 0.87 s) than with the neutral bolus (6.60 ± 0.58 s, p = 0.01). The amount of residues in the middle and distal esophagus was greater with the acidicbolus. There was no correlation between distal esophageal clearance duration and the amount of residues with the neutral bolus, but there was a positive correlation with the acidic bolus.Conclusion An acidic bolus causes slower bolus transit in the distal esophageal body as compared to a neutral bolus.
机译：背景技术吞咽功能受化学和感官刺激的影响。这项研究的目的是评估健康志愿者中酸性酸味推注对其口服，咽和食道运输的影响。方法对43名年龄在23-71岁的健康受试者进行交通运输的闪烁成像评估。每位受试者随机吞下5 mL的两种液体大剂量：酸性（50 mL水和3 g浓柠檬汁，pH 3.0）和中性（水，pH 6.8），均用37 MBq植酸99m。受试者坐在伽玛照相机的准直仪前，以20帧/秒的速度连续吞咽20 s的每组吞咽图像。结果中性和酸性弹丸的转运和清除时间以及通过口腔和咽部时的残留量。在近端食管中，中性推注（间隙1.40±0.11 s）比酸性推注（1.17±0.07 s，p = 0.04）更长。在远端食道中，酸性推注（间隙10.66±0.87 s）比中性推注（6.60±0.58 s，p = 0.01）更长。酸性推注使食管中部和远端的残留量增加。远端食管清除持续时间与中性推注的残留量之间没有相关性，但与酸性推注呈正相关。结论酸性推注导致远端食道体的推注传输较中性推注慢。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号