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A case of superficial esophageal carcinoma with papilloma resected by en bloc endoscopic submucosal dissection

机译:整体内镜黏膜下剥离术切除浅表性食管癌并乳头状瘤1例

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摘要

A 71-year-old man underwent upper gastrointestinal endoscopy, and a slightly protruded lesion was detected 26 cm from the incisors. Biopsy specimen revealed chronic esophagitis. One year later, re-examination with upper gastrointestinal endoscopy showed persistence of the protruded lesion and also new findings of a slightly depressed and erythematous lesion at the opposite side. He was admitted to our hospital, and histological examination of the biopsy specimens from upper gastrointestinal endoscopy revealed concomitant squamous cell papilloma and squamous cell carcinoma. [~(18)F]-fluorode-oxyglucose (FDG) accumulated in the squamous cell papilloma and/or in the mucosal squamous cell cancer. Endoscopic submucosal dissection was performed. Human papillomavims (HPV) 16/18 was not detected in either lesion. Concomitant esophageal papilloma and esophageal squamous cell carcinoma is extremely rare. Additional study is required to characterize the etiology, diagnosis (including FDG accumulation), and clinical course of this phenomenon. The relationship between HPV infection and esophageal squamous cell carcinoma is reviewed.
机译:一名71岁的男子接受了上消化道内镜检查,在距门齿26厘米处发现了一个轻微突出的病变。活检标本显示慢性食管炎。一年后,再次用上消化道内窥镜检查发现突出的病灶持续存在,并且在对侧又发现了轻微的凹陷和红斑病灶。他被送进我们的医院,对上消化道内窥镜检查的活检标本进行组织学检查发现鳞状上皮乳头状瘤和鳞状上皮癌。 [〜(18)F]-氟脱氧葡萄糖(FDG)积累在鳞状细胞乳头状瘤和/或粘膜鳞状细胞癌中。内镜下黏膜下剥离术。在任一病灶中均未检测到人乳头瘤病毒(HPV)16/18。并发食管乳头状瘤和食管鳞状细胞癌极为罕见。需要进一步研究以表征该现象的病因,诊断(包括FDG积累)和临床过程。综述了HPV感染与食管鳞状细胞癌之间的关系。

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