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首页> 外文期刊>Esophagus >Amelanotic primary malignant melanoma of the esophagus: report of a case treated with minimally invasive esophagectomy and adjuvant chemotherapy
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Amelanotic primary malignant melanoma of the esophagus: report of a case treated with minimally invasive esophagectomy and adjuvant chemotherapy

机译：食道羊膜原发性恶性黑色素瘤：一例经微创食管切除术和辅助化疗治疗的报告

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Amelanotic primary malignant melanoma of the esophagus (PMME) is extremely rare. We report a case of amelanotic PMME that was accurately diagnosed and subsequently treated by radical resection with adjuvant chemotherapy. A 69-year-old woman was admitted to our hospital because of dysphagia. Endoscopic examination revealed a tumor without pigmentation in the upper thoracic esophagus, and melanosis in the lower thoracic esophagus. Tumor biopsy showed proliferation of malignant spindle cells with conspicuous nucleoli. Immunohistochemically, the tumor cells were positive for melanosomes (HMB45). The tumor was diagnosed as PMME. Positron emission tomography and computed tomography showed accumulation of the tracer only in the primary lesion. The preoperative diagnosis according to the extent of the tumor, whether cancer cells have spread to lymph nodes, and whether metastasis has occurred (TNM) classification was malignant melanoma in the upper third of the esophagus, T2N0M0 stage HA.
机译：食道羊膜原发性恶性黑色素瘤（PMME）极为罕见。我们报告一例经准确诊断并随后通过辅助化疗的根治性切除术治疗的釉质性PMME。一名69岁的女性因吞咽困难入院。内窥镜检查显示，上胸食道无色素沉着，下胸食道黑素沉着。肿瘤活检显示具有明显核仁的恶性梭形细胞增殖。免疫组织化学分析，肿瘤细胞对黑素体（HMB45）呈阳性。肿瘤被诊断为PMME。正电子发射断层扫描和计算机断层扫描显示示踪剂仅在原发灶处积聚。术前根据肿瘤的范围，癌细胞是否已扩散到淋巴结以及是否已发生转移（TNM）进行分类，这是食管上三分之一（T2N0M0期）的恶性黑色素瘤。

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