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首页> 外文期刊>European journal of clinical microbiology and infectious diseases: Official publication of the European Society of Clinical Microbiology >Epidemiology of Acinetobacter spp.-associated healthcare infections and colonization among children at a tertiary-care hospital in Saudi Arabia: a 6-year retrospective cohort study.
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Epidemiology of Acinetobacter spp.-associated healthcare infections and colonization among children at a tertiary-care hospital in Saudi Arabia: a 6-year retrospective cohort study.

机译：沙特阿拉伯一家三级医院的儿童不动杆菌属相关医疗保健感染和定植流行病学：一项为期6年的回顾性队列研究。

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摘要

A retrospective cohort study was conducted among hospitalized children less than 12 years of age who had Acinetobacter spp. isolated from ≥1 cultures between October 2001 and December 2007 at King Abdulaziz Medical City in Riyadh, Saudi Arabia. Children with multidrug-resistant (MDR) Acinetobacter spp. healthcare-associated infections (HAIs) were compared to children with antimicrobial-susceptible Acinetobacter spp. HAIs and to children colonized with Acinetobacter. Children with MDR Acinetobacter spp. HAIs were older (p?=?0.01), more likely to be admitted to an intensive care unit (ICU) (p?=?0.06), and had a higher mortality rate (p?=?0.02) than colonized children. Children with MDR Acinetobacter spp. HAIs were older than children with antimicrobial-susceptible Acinetobacter spp. HAIs (p?=?0.0004), but their mortality rates were similar. Among children with MDR Acinetobacter spp. HAIs, burn injuries were the most common underlying illness. HAIs caused by MDR or susceptible Acinetobacter spp. occurred after prolonged hospitalization, suggesting nosocomial acquisition. Patients infected with MDR Acinetobacter spp. frequently received inappropriate empiric therapy (73.9 %). Further studies are needed in order to identify effective strategies to prevent nosocomial transmission and effective ways of improving patient outcomes.
机译：一项回顾性队列研究在住院的小于十二岁的不动杆菌属儿童中进行。于2001年10月至2007年12月间在沙特阿拉伯利雅得阿卜杜勒阿齐兹国王医学城内从≥1种文化中分离出来。儿童多药耐药（MDR）不动杆菌属。将与医疗相关的感染（HAIs）与具有抗菌敏感性不动杆菌属的儿童进行比较。 HAIs和不动杆菌属定植的儿童。儿童耐多药不动杆菌属。 HAIs年龄较大（p？=？0.01），更可能被重症监护病房（ICU）接纳（p？=？0.06），并且死亡率比定居儿童高（p？=？0.02）。儿童耐多药不动杆菌属。 HAIs的年龄比患有抗生素敏感性不动杆菌属的儿童大。 HAI（p？=？0.0004），但其死亡率相似。在患有耐多药性不动杆菌属的儿童中。 HAI，烧伤是最常见的潜在疾病。由MDR或易感不动杆菌属引起的HAI。长期住院后发生，提示医院获得。受耐多药不动杆菌属感染的患者。经常接受不适当的经验疗法（73.9％）。为了确定预防院内传播的有效策略以及改善患者预后的有效方法，需要进行进一步的研究。

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